|
CHR
|
CYTOBAND
|
Deletion START
|
Deletion END
|
No OF T WITHOUT EGFR MUT
|
No OF T WITH EGFR MUT
|
KNOWN GENES WITHIN REGIONS
|
GENES
| | |
|---|
|
2
|
2q36.3
|
227428860
|
228480608
|
0
|
2(1LOH+1HOMO)
|
3
|
RHBDD1
|
COL4A4
|
COL4A3
|
|
9
|
9p21.1
|
21701815
|
22685593
|
2 (LOH)
|
7(4LOH+3HOMO)
|
3
|
CDKN2A/2B
|
MTAP
|
DMRTA1
|
|
12
|
12q13.13
|
49778776
|
50467951
|
1(LOH)
|
1HOMO
|
3
|
TFCP2
|
POU6F1
|
DAZAP2
|
|
18
|
18q12.1
|
25534701
|
27580619
|
2(LOH)
|
3(2LOH+1HOMO)
|
3
|
CDH2
|
DSC3
|
DSG2
|
|
18
|
18q21.2
|
46939466
|
49883403
|
2(LOH)
|
4(3LOH+1HOMO)
|
2
|
RKHD2
|
DCC
| |
- Homozygous deletion were validated by real time quantitative PCR for CDKN2A, DCC, DSC3 and DSG2.
