Table 1 Breast cancer gene-signatures.
From: Pathway analysis reveals functional convergence of gene expression profiles in breast cancer
Gene-signature | Number of genes | number of samples | Experiment summary |
|---|---|---|---|
1. 70-gene profile [1] | 70 | 78 | Inkjet oligonucleotide array on 25,000 genes |
2. Wound-response [4] | 512 | 50 | cDNA microarrays profiled over 36,000 genes |
427 | 78 | cDNA microarrays on a core set of 8,102 genes | |
4. meta-90 [11] | 90 | 305 | Integrative analysis of 4 microarray studies on a set of 2,555 genes |
ER+ signature | Â | ||
5. Recurrence score [14] | 21 | 2892 | RT-PCR on 250 genes selected from the literature |
6. Wang ER+ profile [18] | 60 | 80 | Affymetrix GeneChips on 22,000 transcripts |