Table 4 Five common pathway sets (MsigDB) across the four breast cancer gene signatures (significance of overlap, P = 0.04).
From: Pathway analysis reveals functional convergence of gene expression profiles in breast cancer
| Â | 70 Gene | Wound Response | Intrinsic Subtype | Meta90 | Â |
|---|---|---|---|---|---|
Common GeneSet | No. of mapped genes (Enrichment p-value**) | Description | |||
breast cancer estrogen signaling | 1 (0.07) | 11 (0.001) | 11 (0.22) | 4 (0.11) | GEArray |
EMT DOWN | 1 (0.02) | 2 (0.19) | 4 (0.29) | 1 (0.21) | Jechlinger et al 2003 |
CR DNA MET AND MOD | 1 (0.01) | 1 (0.24) | 3 (0.24) | 1 (0.12) | PNAS 2007 |
SA REG CASCADE OF CYCLIN EXPR | 1 (0.006) | 1 (0.12) | 2 (0.23) | 1 (0.07) | SigmaAldrich |
reckPathway | 1 (0.005) | 1 (0.09) | 1 (0.28) | 1 (0.09) | BioCarta |