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Table 4 Five common pathway sets (MsigDB) across the four breast cancer gene signatures (significance of overlap, P = 0.04).

From: Pathway analysis reveals functional convergence of gene expression profiles in breast cancer

  70 Gene Wound Response Intrinsic Subtype Meta90  
Common GeneSet No. of mapped genes (Enrichment p-value**) Description
breast cancer estrogen signaling 1 (0.07) 11 (0.001) 11 (0.22) 4 (0.11) GEArray
EMT DOWN 1 (0.02) 2 (0.19) 4 (0.29) 1 (0.21) Jechlinger et al 2003
CR DNA MET AND MOD 1 (0.01) 1 (0.24) 3 (0.24) 1 (0.12) PNAS 2007
SA REG CASCADE OF CYCLIN EXPR 1 (0.006) 1 (0.12) 2 (0.23) 1 (0.07) SigmaAldrich
reckPathway 1 (0.005) 1 (0.09) 1 (0.28) 1 (0.09) BioCarta
  1. ** Hypergeometic test enrichment P-value adjusted for multiple testing.