Table 1 Name and function of the differentially expressed genes that best distinguish samples by cell type variable
GENE | UniGene ID | GENE NAME | FUNCTION |
|---|---|---|---|
ADAMTS1 | Hs.534115 | disintegrin-like and metalloprotease (reprolysin type) | negative regulation of cell proliferation |
ARHGEF10 | Hs.443460 | Rho guanine nucleotide exchange factor (GEF) 10 | GTPase activator activity |
CD44 | Hs.502328 | CD44 antigen | cell adhesion |
CITED1 | Hs.40403 | Cbp/p300-interacting transactivator | transcription regulator activity |
CREG | Hs.5710 | cellular repressor of E1A-stimulated genes 1 | cell proliferation |
CSTA | Hs.518198 | cystatin A (stefin A) | cysteine protease inhibitor activity |
D4S234E | Hs.518595 | DNA segment on chromosome 4 (unique) 234 expressed sequence | dopamine receptor signaling pathway |
DHRS3 | Hs.289347 | dehydrogenase/reductase (SDR family) member 3 | fatty acid metabolism |
EPB41L1 | Hs.437422 | erythrocyte membrane protein band 4.1-like 1 | structural molecule activity |
FLJ20105 | Hs.47558 | FLJ20105 | regulation of transcription |
FLJ21511 | Hs.479703 | FLJ21511 | unknown function |
FLJ21616 | Hs.591836 | FLJ21616 | regulation of transcription |
FLJ30525 | Hs.7962 | FLJ30525 | unknown function |
GALNT11 | Hs.647109 | UDP-N-acetyl-alpha-D-galactosamine | transferase activity, transferring glycosyl groups |
GC20 | Hs.315230 | translation factor sui1 homolog | regulation of translational initiation |
GLDC | Hs.584238 | glycine dehydrogenase | glycine metabolism |
GSR | Hs.271510 | glutathione reductase | glutathion metabolism |
HBP17 | Hs.1690 | fibroblast growth factor binding protein 1 | regulation of cell proliferation |
INHBA | Hs.28792 | inhibin, beta A | cell cycle arrest, negative regulation of immune cell differentiation |
JPH3 | Hs.592068 | junctophilin 3 | unknown function |
KIAA0368 | Hs.368255 | KIAA0368 | ER-associated protein catabolism |
KLK7 | Hs.151254 | kallikrein 7 (chymotryptic, stratum corneum) | epidermis development, proteolysis and peptidolysis, chymotrypsin activity |
LCN2 | Hs.204238 | lipocalin 2 (oncogene 24p3) | transporter activity |
LXN | Hs.478067 | latexin | enzyme inhibitor activity |
MAL2 | Hs.201083 | T-cell differentiation protein 2 | Unknown function |
MCM2 | Hs.477481 | minichromosome maintenance deficient 2 | cell cycle |
MGC45400 | Hs.389734 | transcription elongation factor A (SII)-like 8 | translation elongation factor activity |
MGEA5 | Hs.500842 | meningioma expressed antigen 5 (hyaluronidase) | glycoprotein catabolism |
MYO5B | Hs.200136 | acetyl-Coenzyme A acyltransferase 2 | fatty acid metabolism |
NMES1 | Hs.112242 | normal mucosa of esophagus specific 1 | unknown function |
NMU | Hs.418367 | neuromedin U | neuropeptide signaling pathway, digestion |
NT5E | Hs.153952 | 5'-nucleotidase, ecto (CD73) | DNA metabolism |
OAS1 | Hs.524760 | 2',5'-oligoadenylate synthetase 1 | immune response to viral infections |
ODC1 | Hs.467701 | ornithine decarboxylase 1 | polyamine biosynthesis |
PARVA | Hs.607144 | parvin, alpha | cell adhesion, actin binding |
PEX3 | Hs.7277 | peroxisomal biogenesis factor 3 | peroxisome organization |
PI3 | Hs.112341 | protease inhibitor 3, skin-derived (SKALP) | elastase-specific inhibitor |
PLAU | Hs.77274 | plasminogen activator | chemotaxis |
PPGB | Hs.517076 | protective protein for beta-galactosidase | intracellular protein transport |
PROS1 | Hs.64016 | protein S (alpha) | cell adhesion, endopeptidase inhibitor activity |
PRSS11 | Hs.501280 | protease, serine, 11 (IGF binding) | insulin-like growth facto binding, regulation of cell growth |
RARRES1 | Hs.131269 | retinoic acid receptor responder | negative regulation of cell proliferation |
RDH-E2 | Hs.170673 | epidermal retinal dehydrogenase 2 | oxidoreductase activity |
RPL15 | Hs.381219 | ribosomal protein L15 | protein biosynthesis |
RUTBC3 | Hs.474914 | RUN and TBC1 domain containing 3 | unknown function |
S100P | Hs.440880 | S100 calcium binding protein P | cell cycle progression and differentiation |
SEPT10 | Hs.469615 | septin 10 | cell cycle |
SF3B4 | Hs.516160 | myotubularin related protein 11 | inositol or phosphatidylinositol phosphatase activity |
SIMP | Hs.475812 | immunodominant MHC-associated peptides | protein amino acid glycosylation |
SMOC2 | Hs.487200 | SPARC related modular calcium binding | calcium ion binding |
SOD2 | Hs.487046 | superoxide dismutase 2 | age-dependent response to reactive oxygen species, cellular defense response |
STAF65 (gamma) | Hs.6232 | SPTF-associated factor 65 gamma | regulation of transcription, DNA- dependent |
SYTL3 | Hs.436977 | synaptotagmin-like 3 | intracellular protein transport |
TFRC | Hs.529618 | transferrin receptor (p90, CD71) | endocytosis |
TGFB1 | Hs.645227 | transforming growth factor, beta 1 | cell proloferation |
TPD52 | Hs.368433 | tumor protein D52 | morphogenesis |
TPX2 | Hs.244580 | microtubule-associated protein homolog | cell proliferation |
TRIM31 | Hs.493275 | tripartite motif-containing 31 | protein ubiquitination, ubiquitin ligase activity |
YME1L1 | Hs.499145 | YME1-like 1 (S. cerevisiae) | protein catabolism |
ZNF198 | Hs.644041 | zinc finger protein 198 | regulation of transcription, DNA- dependent |