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Table 2 Name and function of the differentially expressed genes that best distinguish samples by TNF treatment variable

From: Characterization of global transcription profile of normal and HPV-immortalized keratinocytes and their response to TNF treatment

GENE UniGene ID GENE NAME FUNCTION
ADORA2b Hs.167046 adenosine A2b receptor activation of MAPK
AKAP1 Hs.463506 A kinase (PRKA) anchor protein 1 RNA binding
BTG2 Hs.519162 BTG family, member 2 negative regulation of cell proliferation
C3 Hs.529053 complement component 3 inflammatory response
CCL20 Hs.75498 chemokine (C-C motif) ligand 20 inflammatory response
CD44 Hs.502328 CD44 antigen cell adhesion
cig5 Hs.17518 radical S-adenosyl methionine domain containing 2 Catalytic activity
CLCA4 Hs.546343 chloride channel, calcium activated, family member 4 chloride transport
DC-UbP Hs.179852 dendritic cell-derived ubiquitin-like protein Protein modification
FAD104 Hs.159430 fibronectin type III domain containing 3B cell differentiation
FLJ21511 Hs.479703 FLJ21511 Unknown function
FMNL3 Hs.179838 formin-like 3 cell organization and biogenesis
GFPT2 Hs.30332 glutamine-fructose-6-phosphate transaminase 2 carbohydrate biosynthesis
HLA-F Hs.519972 major histocompatibility complex, class I, F antigen presentation, endogenous antigen
IL1F9 Hs.211238 interleukin 1 family, member 9 inflammatory response
INHBA Hs.28792 inhibin, beta A cell cycle arrest, negative regulation of immune cell differentiation
KIAA0303 Hs.133539 microtubule associated serine/threonine kinase family member 4 protein kinase activity
KIAA1279 Hs.279580 KIAA1279 Unknown function
LAP3 Hs.479264 leucine aminopeptidase 3 Protein metabolism
MARCKS Hs.75061 MARCKS-like 1 calmodulin binding, macrophage activation
MGAT4B Hs.437277 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B cytokine activity
MGC45400 Hs.389734 transcription elongation factor A (SII)-like 8 translation elongation factor activity
MMP9 Hs.297413 matrix metalloproteinase 9 proteolysis and peptidolysis
NFKBIA Hs.81328 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha cytoplasmic sequestering of NF-kappaB
NMES1 Hs.112242 normal mucosa of esophagus specific 1 Unknown function
OAS1 Hs.524760 2',5'-oligoadenylate synthetase 1 immune response to viral infections
PLAU Hs.77274 plasminogen activator chemotaxis
RDH-E2 Hs.170673 epidermal retinal dehydrogenase 2 oxidoreductase activity
RFX5 Hs.166891 regulatory factor X, 5 inflammatory response, HLA class II expression
RIG-1 Hs.17466 retinoic acid receptor responder (tazarotene induced) 3 negative regulation of cell proliferation
RIPK2 Hs.103755 receptor-interacting serine-threonine kinase 2 inflammatory response
SASH1 Hs.193133 SAM and SH3 domain containing 1 Negative regulation of cell cycle
SDCBP Hs.200804 syndecan binding protein (syntenin) intracellular signaling cascade, interleukin-5 receptor binding
SEC24A Hs.211612 SEC24 related gene family, member A intracellular protein transport
SERPINB2 Hs.514913 encoding serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 anti-apoptosis
SF3B4 Hs.412818 myotubularin related protein 11 RNA splicing
SOD2 Hs.487046 superoxide dismutase 2 age-dependent response to reactive oxygen species, cellular defense response
TMSB4 Hs.522584 thymosin, beta 4, X-linked cytoskeleton organization and biogenesis
VMP1 Hs.444569 transmembrane protein 49 Unknown function
  1. *Genes are listed in alphabetical order. The cutoff p-value was set as <10-2,9.