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Table 3 List of differentially expressed genes that best distinguish TNF-resistant cells (HPV18) from TNF-sensitive cells (PHK and HPV16), in normal culture conditions or upon treatment with TNF for 3 hours

From: Characterization of global transcription profile of normal and HPV-immortalized keratinocytes and their response to TNF treatment

   (PHK and HPV16) vsHPV18 (PHK_TNF and HPV16_TNF) vsHPV18_TNF
GENE GENE NAME FOLD p VALUE FOLD p VALUE
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.592 0.001384 ---- ----
ACBD5 acyl-Coenzyme A binding domain containing 5 ---- ---- 0.378 0.00086
ALDH3A2 encoding aldehyde dehydrogenase 3 family, member A2 1.623 0.00122 ---- ----
APG12L APG12 autophagy 12-like (S. cerevisiae) 1.739 0.000924 ---- ----
APPBP1 amyloid beta precursor protein binding protein 1 0.540 0.000283 ---- ----
ARF4L ADP-ribosylation factor 4-like ---- ---- 0.578 5.70E-05
BCLAF1 BCL2-associated transcription factor 1 0.611 0.000876 ---- ----
BOC brother of CDO ---- ---- 2.337 6.00E-06
CCNA2 cyclin A2 0.577 0.000604 ---- ----
CDCA2 cell division cycle associated 2 ---- ---- 0.539 7.20E-05
CDK2AP1 CDK2-associated protein 1 ---- ---- 1.523 0.000148
CPSF3 cleavage and polyadenylation specific factor 3 0.586 0.000466 ---- ----
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.499 0.001386 ---- ----
DEK DEK oncogene 0.480 0.000278 ---- ----
FAM31C family with sequence similarity 31, member C ---- ---- 2.548 0.000663
FLJ20105 hypothetical protein LOC54821 0.026 5.00E-06 0.029 2.00E-06
GALNAC4S-6ST B cell RAG associated protein 1.827 0.000145 1.673 0.000215
H105E3 encoding NAD(P) dependent steroid dehydrogenase-like ---- ---- 0.569 6.80E-05
HLCS holocarboxylase synthetase ---- ---- 1.551 0.00011
JPH3 junctophilin 3 0.154 0.000192 ---- ----
KIAA0795 kelch-like 18 (Drosophila) 0.857 0.001325 ---- ----
KIAA1023 IQ motif containing E 1.575 0.000723 ---- ----
KIF1B kinesin family member 1B ---- ---- 0.570 0.000632
KLK7 encoding kallikrein 7 (chymotryptic, stratum corneum) 0.421 0.000416 0.374 2.30E-05
LCN2 lipocalin 2 (oncogene 24p3) ---- ---- 0.216 0.000686
LOC151242 protein phosphatase 1, regulatory (inhibitor) 1.928 0.000268 ---- ----
Lrp2bp low density lipoprotein receptor-related protein binding protein 0.629 0.000574 ---- ----
MAPRE1 encoding microtubule-associated protein, RP/EB family, member 1 0.410 0.001068 0.503 4.20E-05
MBD2 methyl-CpG binding domain protein 2 0.680 0.001247 ---- ----
MGC35048 hypothetical protein MGC35048 ---- ---- 0.499 0.000211
MRPS6 mitochondrial ribosomal protein S6 ---- ---- 1.460 0.000161
MYO5B acetyl-Coenzyme A acyltransferase 2 0.353 0.000104 0.292 4.10E-05
NMES1 normal mucosa of esophagus specific 1 0.324 0.000294 0.244 7.00E-06
NPR2 encoding natriuretic peptide receptor B/guanylate cyclase B ---- ---- 0.435 0.000234
ODC1 ornithine decarboxylase 1 1.660 0.000886 ---- ----
PI3 protease inhibitor 3, skin-derived (SKALP) 0.213 0.000274 0.207 1.80E-05
PROS1 protein S (alpha) 1.807 0.000633 ---- ----
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.478 0.000385 0.497 1.80E-05
RRAGA Ras-related GTP binding A ---- ---- 1.510 0.000301
RUTBC3 RUN and TBC1 domain 3 0.518 0.000704 0.450 0.000131
S100P S100 calcium binding protein P 0.101 0 0.102 0
SDCBP syndecan binding protein (syntenin) 0.456 0.000395 ---- ----
SFRP1 secreted frizzled-related protein 1 ---- ---- 0.502 5.10E-05
SLC35B3 solute carrier family 35, member B3 ---- ---- 1.990 0.000304
STAF65 (gamma) SPTF-associated factor 65 gamma 0.021 1.00E-06 0.028 0
THBS1 thrombospondin 1 ---- ---- 2.712 0.000225
VMP1 likely ortholog of rat vacuole membrane protein 1 ---- ---- 1.547 0.000899
YME1L1 YME1-like 1 (S. cerevisiae) 0.373 2.60E-05 0.333 5.00E-06
  1. *Genes are listed in alphabetical order. Underlined genes were identified as differentially expressed between TNF sensitive and TNF resistant cells in both culture conditions.