A. Genome-wide overview of copy number alterations in 38 bladder tumors. Each row represents a separate tumor sample, with case numbers and tumor grades indicated to the left. Each column shows one of the 32,433 different BAC clones on the microarray, ordered from 1pter to Yqter. Test over reference fluorescence ratios (moving average, symmetric 4-nearest neighbors) based on a log2 pseudocolor scale (indicated) are shown. B. Genome-wide imbalance frequency plot for G1/G2 and G3 tumors. Gains and losses are as defined in materials and methods. Red, gains; green, losses.