Table 1 Consistently differentially expressed genes at all measurements after LSR knock down by both LSR siRNAs (log2 scale).
Location | Gene | LSR1 | LSR2 | |||||
|---|---|---|---|---|---|---|---|---|
18 h | 48 h | 72 h | 18 h | 48 h | 72 h | |||
Cytoplasm | AKAP12 | A kinase (PRKA) anchor protein (gravin) 12 | 1.2 | 1.8 | 1.9 | 1.1 | 2.1 | 2.1 |
Extracell. Space | FST | follistatin | 1.8 | 3.2 | 2.8 | 1.9 | 3.9 | 3.6 |
APLP2 | amyloid beta (A4) precursor-like protein 2 | 1.3 | 1.6 | 1.1 | 1.3 | 1.6 | 1.2 | |
IL1A | interleukin 1, alpha | 1.3 | 2.0 | 1.7 | 1.4 | 2.1 | 2.2 | |
CYR61 | cysteine-rich, angiogenic inducer, 61 | 1.1 | 2.6 | 2.2 | 1.0 | 2.3 | 2.6 | |
EDN1 | endothelin 1 | 1.2 | 3.1 | 1.8 | 1.2 | 2.7 | 2.6 | |
GLIPR1 | GLI pathogenesis-related 1 (glioma) | 1.4 | 2.2 | 2.6 | 1.7 | 2.8 | 2.8 | |
PTHLH | parathyroid hormone-like hormone | 1.5 | 3.3 | 3.8 | 1.0 | 3.0 | 3.2 | |
Nucleus | EGR1 | early growth response 1 | 2.0 | 3.7 | 2.5 | 2.9 | 1.6 | 3.5 |
MYOCD | myocardin | 1.1 | 1.9 | 2.1 | 1.1 | 1.5 | 1.8 | |
Plasma Membrane | TSPAN8 | tetraspanin 8 | -1.1 | -1.9 | -2.5 | -1.9 | -3.1 | -3.0 |
MALL | mal, T-cell differentiation protein-like | 1.7 | 1.3 | 1.1 | 1.4 | 1.5 | 1.3 | |
NEXN | nexilin (F actin binding protein) | 1.4 | 1.5 | 1.3 | 1.4 | 1.7 | 1.4 | |
LSR | lipolysis stimulated lipoprotein receptor | -3.6 | -2.8 | -2.4 | -2.6 | -1.6 | -1.3 | |
Unknown | TMCO1 | transmembrane and coiled-coil domains 1 | 2.0 | 1.8 | 1.4 | 1.9 | 1.7 | 1.3 |
TRIM31 | tripartite motif-containing 31 | -1.3 | -2.0 | -1.5 | -1.2 | -1.9 | -1.7 |