Figure 6

Range of expression of differentially expressed 3q genes for OV-90. The expression values of all of the growth conditions are shown for genes exhibiting greater than 3-fold differences in gene expression between the monolayer cultures and any alternative growth condition of OV-90; and greater than 3-fold differences between the maximum and minimum value of expression determined for any growth condition for each OV-90. The growth conditions are abbreviated as follows: monolayer culture (L), and alternative growth conditions consisting of spheroid cultures (S), xenograft tumors derived from subcutaneous (TSC) or intraperitoneal (TIP) injection sites in nude mice, and monolayer cultures derived from these tumors (LSC and LIP). For comparative purposes the expression values of the monolayer cultures are linked with a line. The gene name and probe set number are indicated, and are ordered (not to scale) based on the Human Genome Browser March 2006 (hg 18) assembly (UCSC Genome Bioinformatics database). The expression profiles are organized relative to the position of the probe sets (genes) for the 3qcen – 3qtel chromosome arm. The arrows indicate the genes exhibiting differential expression greater than 3-fold in any comparative analyses that were found in common with all three EOC cell lines.