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Figure 4 | BMC Medical Genomics

Figure 4

From: Role of Caveolin 1, E-Cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells

Figure 4

mRNA levels of CAV1, ENO2, PKCα and DHFR upon siRNA treatment of MTX-resistant cells. Treatments with increasing amounts of each siRNA were performed in MTX-resistant HT29 cells. Forty-eight hours later, mRNA levels for each gene were determined and expressed as percentages of the untreated control (A, CAV1; B, ENO2; C, PKCα and D, DHFR). A non-related (NR) siRNA was used as negative control. Results are depicted taking into account the relative gene expression in the resistant cells (% of the sensitive cells). Values are the mean of three independent experiments ± SE.

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