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Table 4 Hyperclustered TRANSFAC and GO Category Annotations

From: Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males

Cluster

TRANSFAC Annotations

   

A

V$POU3F2_02

   
 

V$ISRE_01: interferon-stimulated response element

   
 

V$DEAF1_01

   
 

V$E2F1_Q3_01

   
 

V$MAZR_01: MAZ related factor

   
 

V$KROX_Q6

   
 

V$E2F1DP1_01: E2F-1:DP-1 heterodimer

   
 

V$HNF1_Q6

   
 

V$E2F_Q3_01

   
 

V$E2F1_Q6: E2F-1

   

Cluster

Common GO Parent Node

Gene Ontology

GO Level

GO Name

B

signal transduction [4] GO:0007165

GO:0007264

6

small GTPase mediated signal transduction

  

GO:0007165

4

signal transduction

  

GO:0007242

5

intracellular signaling cascade

C

programmed cell death [5] GO:0012501

GO:0006917

8

induction of apoptosis

  

GO:0012502

7

induction of programmed cell death

  

GO:0043068

6

positive regulation of programmed cell death

  

GO:0043065

7

positive regulation of apoptosis

  

GO:0050794

3*

regulation of cellular process

  

GO:0016265

3*

death

  

GO:0008219

4*

cell death

  

GO:0012501

5

programmed cell death

  

GO:0006915

6

apoptosis

  

GO:0043067

5

regulation of programmed cell death

  

GO:0042981

6

regulation of apoptosis

D

response to stress [4] GO:0006950

GO:0006950

4

response to stress

E

macromolecule metabolic process [4] GO:0043170

GO:0006493

9

O-linked glycosylation

  

GO:0043170

4

macromolecule metabolism

  

GO:0044260

5

cellular macromolecule metabolism

  

GO:0019222

4*

regulation of metabolism

F

transcription [6] GO:0006350

GO:0006350

6

transcription

  

GO:0045449

6

regulation of transcription

  

GO:0019219

5*

regulation of nucleo-base, -side, -tide and nucleic acid metabolism

  

GO:0006355

7

regulation of transcription, DNA-dependent

  

GO:0006351

7

transcription, DNA-dependent

G

cell cycle process [6] GO:0022402

GO:0000082

7

G1/S transition of mitotic cell cycle

  

GO:0000132

11

mitotic spindle orientation

H

mevalonate transport [8] GO:0015728

GO:0015728

8

mevalonate transport

  1. * Node is not a child of the parent node for this group