| | |
Dataset
|
|---|
|
Gene signature model
|
Number of genes used in the classification model
|
Training and testing: Wang dataset [8]
|
Independent validation: Miller dataset [22]
|
Independent validation: Pawitan dataset [7]
|
|---|
|
The 70-gene signature
|
51
|
6.1E-05
|
0.057
|
0.051
|
|
Breast cancer
|
232
|
2.6E-09
|
0.0012
|
0.0019
|
|
Cell Cycle
|
108
|
1.4E-06
|
0.0050
|
0.0046
|
|
Random
|
232
|
1.8E-13
|
0.14
|
0.52
|
- The numbers represent the log-rank test P values in Kaplan-Meier analysis in the good and poor prognosis groups predicted by the Amsterdam 70-gene signature, the breast cancer gene set, the cell cycle gene set classifier, and the randomly selected gene set respectively.
