Table 2 Association analysis of tag SNPs used to cover the LD block containing LRAT.
From: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling
SNP ID | Position (Mb on Chr 4) | Minor Allele | Minor Allele Freq Cases | Minor Allele Freq Controls | Minor Allele Freq 1958 | p Cases vs MRC Cons | OR Cases vs MRC Cons (95% CI) | p Cases vs Comb Cons | OR Cases vs Comb Cons (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
Rs12501328 | 156,019,936 | G | 0.10 | 0.08 | 0.07 | 0.02661 | 1.27 (1–1.6) | 0.0032 | 1.32 (1.1 – 1.6) |
Rs201825 | 156,024,540 | C | 0.52 | 0.44 | 0.46 | 1.65E-06 | 1.34 (1.2–1.5) | 6.12E-07 | 1.3 (1.2 – 1.4) |
Rs201824 | 156,026,315 | T | 0.40 | 0.35 |  | 0.00066 | 1.24 (1.1–1.4) | N/A | N/A |
Rs201823 | 156,026,490 | G | 0.40 | 0.35 | 0.37 | 0.00042 | 1.24 (1.1–1.4) | 0.0004 | 1.21 (1.1 – 1.3) |
Rs156500 | 156,034,920 | C | 0.13 | 0.11 |  | 0.09457 | 1.17 (1–1.4) | N/A | N/A |
Rs156501 | 156,035,950 | A | 0.22 | 0.19 | 0.19 | 0.01635 | 1.2 (1–1.4) | 0.0058 | 1.2 (1.1 – 1.4) |
Rs149225 | 156,040,821 | C | 0.42 | 0.40 |  | 0.34900 | 1.06 (0.9–1.2) | N/A | N/A |