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Table 3 Distribution of p-values of individually genotyped SNPs (excluding those in the region of APOE).

From: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

  

P-Value Range

Selection Category

N

< 0.05

0.05 – 0.005

5 × 10-3- 5 × 10-4

5 × 10-4- 5 × 10-5

5 × 10-5- 5 × 10-6

ALL SNPs

109

74 (67.9%)

38 (34.9%)

22 (20.2%)

11 (10.1%)

3 (2.8%)

CLUSTERS

33/58

28 (84.8%)

12 (36.4%)

8 (24.2%)

5 (15.2%)

3 (9.1%)

COMB

66/115

44 (66.6%)

22 (33.3%)

13 (19.7%)

8 (12.1%)

1 (1.5%)

FREQ

46/136

24 (52.2%)

13 (28.3%)

9 (19.6%)

2 (4.3%)

0 (0%)

  1. Selection category gives the method used to choose SNP for individual genotyping (see text for description). N: number of SNPs tested in each selection category. Note: of the 66 SNPs in the COMB category, 11 and 25 SNPs respectively had been identified by the CLUSTER and FREQ methods.