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Table 3 Distribution of p-values of individually genotyped SNPs (excluding those in the region of APOE).

From: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

   P-Value Range
Selection Category N < 0.05 0.05 – 0.005 5 × 10-3- 5 × 10-4 5 × 10-4- 5 × 10-5 5 × 10-5- 5 × 10-6
ALL SNPs 109 74 (67.9%) 38 (34.9%) 22 (20.2%) 11 (10.1%) 3 (2.8%)
CLUSTERS 33/58 28 (84.8%) 12 (36.4%) 8 (24.2%) 5 (15.2%) 3 (9.1%)
COMB 66/115 44 (66.6%) 22 (33.3%) 13 (19.7%) 8 (12.1%) 1 (1.5%)
FREQ 46/136 24 (52.2%) 13 (28.3%) 9 (19.6%) 2 (4.3%) 0 (0%)
  1. Selection category gives the method used to choose SNP for individual genotyping (see text for description). N: number of SNPs tested in each selection category. Note: of the 66 SNPs in the COMB category, 11 and 25 SNPs respectively had been identified by the CLUSTER and FREQ methods.