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Table 2 The 10 most upregulated genes after at 36 hours after carboplatin exposure compared to baseline.

From: Carboplatin-induced gene expression changes in vitroare prognostic of survival in epithelial ovarian cancer

GENE NAME

GENE SYMBOL

FOLD CHANGE

Activating transcription factor 3

ATF3

17.2

Interleukin 8

IL8

13.4

Interleukin 6 (interferon, beta 2)

IL6

8.5

Growth differentiation factor 15

GDF15

7

Chromosome 1 open reading frame 79

C1orf79

6.3

Pentraxin-related gene, rapidly induced by IL-1 beta

PTX3

6.3

v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

MAFF

6

Claudin 1

CLDN1

5.9

Growth arrest and DNA-damage-inducible, alpha

GADD45A

5.7

Tumor necrosis factor, alpha-induced protein 3

TNFAIP3

4.9