Skip to main content

Table 1 Midkine expression is increased in the late stage prostate cancers. Normal and prostate cancer tissue microarray slides were immunohistochemically stained for midkine, using rabbit anti-midkine antibodies and ABC elite kit with DAB substrate, and counterstained by hematoxylin. The grading was assigned to each tissue core by a consensus review of two pathologists.

From: Midkine is a NF-κB-inducible gene that supports prostate cancer cell survival

  

median (range)

 

-

+

++

 

Tissue

No.

Gleason score

P

Midkine stain

P

Normal

18

  

17

1

0

§

Early stage cancer

40

6 (5 – 7)

*

37

3

0

†

Late stage cancer

71

9 (8–10)

 

41

24

6

‡

  1. "-" indicates ≤ 20% of epithelial cells were immunopositive;
  2. "+" indicates 20–50% of epithelial cells were immunopositive;
  3. "++" indicates ≥ 50% of epithelial cells were immunopositive.
  4. * P < 0.001, Gleason scores, early stage cancer v.s. late stage cancer.
  5. § P > 0.05, normal v.s. early stage cancer.
  6. † P < 0.001, early stage cancer v.s. late stage cancer.
  7. ‡ P < 0.001, normal v.s. late stage cancer.
Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us