TY - JOUR AU - Mosig, Sandy AU - Rennert, Knut AU - Büttner, Petra AU - Krause, Siegfried AU - Lütjohann, Dieter AU - Soufi, Muhidien AU - Heller, Regine AU - Funke, Harald PY - 2008 DA - 2008/11/28 TI - Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism JO - BMC Medical Genomics SP - 60 VL - 1 IS - 1 AB - Elevated plasma cholesterol promotes the formation of atherosclerotic lesions in which monocyte-derived lipid-laden macrophages are frequently found. To analyze, if circulating monocytes already show increased lipid content and differences in lipoprotein metabolism, we compared monocytes from patients with Familial Hypercholesterolemia (FH) with those from healthy individuals. SN - 1755-8794 UR - https://doi.org/10.1186/1755-8794-1-60 DO - 10.1186/1755-8794-1-60 ID - Mosig2008 ER -