Figure 3
From: Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism
Principal component analysis (PCA) of gene expression profiles from monocytes. PCA of 35,264 transcripts expressed in monocytes of homozygous FH patients (filled circles), heterozygous FH patients (grey filled circles) and controls (open circles), respectively, that passed pre-filter criteria (described in Material and Methods). Gene signatures in monocytes from FH patients are sufficient to distinguish between FH and healthy controls.