Figure 3
A similarity metric demonstrates the correlation of miR-34b/34c expression between lung cancer cell lines (blue letters). All NSCLC cell lines are in the blue bracket, suggesting that expression of miR-34b/34c/449 might be candidates to classify different types of lung cancer. The calculation of the distance matrix was based on the ΔCT (the average CT of miR-34b/34bN/34c/34cN between two cell lines), so the smaller the ΔCT, the more similar expression levels of the four miRNA sequences are in the two cell lines (more red in the heat map).