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Table 5 Pterostilbene-responsive genes associated with "response to drug" gene ontology category

From: Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol

Accession Gene Ratio p-value Molecular Function
a. Multidrug resistance ABC transporters
   YOR153W PDR5 6.1 6.01 × 10-5 Multidrug resistance ABC transporter
   YOR328W PDR10 7.1 1.01 × 10-4 ABC transporter highly similar to Pdr5p
   YGR281W YOR1 10.3 1.01 × 10-4 Multidrug resistance ABC transporter
   YDR011W SNQ2 8.2 9.71 × 10-6 Multidrug resistance ABC transporter
b. Multidrug resistance MFS transporters
   YNL065W AQR1 2.2 7.19 × 10-3 MFS-multidrug resistance transporter
   YGR224W AZR1 73.4 2.16 × 10-4 MFS plasma membrane transporter
c. Multidrug resistance transcription factors
   YBL005W PDR3 9.5 4.22 × 10-4 Transcriptional activator of the PDR network
   YML007W YAP1 3.1 1.66 × 10-5 Transcription factor required for oxidative stress
   YOR162C YRR1 2.5 9.44 × 10-5 Transcription factor involved in MDR
d. Other drug-responsive genes
   YOR266W PNT1 2.0 0.01 Mitochondrial protein involved in export of proteins
   YNL231C PDR16 6.1 3.54 × 10-4 Pdr17p homolog controlled by Pdr1p
   YGR197C SNG1 4.1 3.7 × 10-4 Protein involved in nitrosoguanidine resistance
   YOR018W ROD1 2.8 8.67 × 10-3 Membrane protein, resistance to o-dinitrobenzene