|
a. Methionine metabolism
|
|
YJR137C
|
ECM17
|
-2.5
|
2.48 × 10-5
|
Sulfite reductase beta subunit
|
|
YKR069W
|
MET1
|
-3.1
|
3.88 × 10-4
|
AdoMet-dependent uroporphyrinogen III transmethylase
|
|
YJR010W
|
MET3
|
-3.8
|
3.5 × 10-4
|
ATP sulfurylase
|
|
YER091C
|
MET6
|
-2.4
|
8.83 × 10-5
|
Cobalamin-independent methionine synthase
|
|
YFR030W
|
MET10
|
-2.1
|
1.5 × 10-3
|
Sulfite reductase alpha subunit
|
|
YGL125W
|
MET13
|
-3.6
|
1.46 × 10-4
|
Methylenetetrahydrofolate reductase
|
|
YKL001C
|
MET14
|
-3.1
|
1.12 × 10-3
|
Adenylylsulfate kinase
|
|
YPR167C
|
MET16
|
-2.0
|
7.56 × 10-4
|
3'-phosphoadenylylsulfate reductase
|
|
YOL064C
|
MET22
|
-2.5
|
1.68 × 10-4
|
Bisphosphate-3'-nucleotidase,
|
|
YLL062C
|
MHT1
|
-3.4
|
6.69 × 10-4
|
S-methylmethionine-homocysteine methyltransferase
|
|
YLR180W
|
SAM1
|
-2.1
|
6.39 × 10-5
|
S-adenosylmethionine synthetase
|
|
b. Sulfur and aspartate family amino acid metabolic processes (in addition to a)
|
|
YNL103W
|
MET4
|
3.0
|
4.01 × 10-4
|
Leucine zipper transcriptional activator
|
|
YPL038W
|
MET31
|
2.2
|
2.45 × 10-3
|
Transcriptional regulator highly homologous to Met32p
|
|
YJR130C
|
STR2
|
2.3
|
2.97 × 10-3
|
Cystathionine gamma-synthase
|
|
YGL184C
|
STR3
|
-3.6
|
4.1 × 10-3
|
Cystathionine beta-lyase
|
|
YJR060W
|
CBF1
|
-3.0
|
1.11 × 10-3
|
Basic helix-loop-helix protein
|
|
YHR025W
|
THR1
|
-2.2
|
2.05 × 10-4
|
Homoserine kinase
|
|
c. All other genes affected under the term "sulfur metabolism"
|
|
YLL060C
|
GTT2
|
2.5
|
8.23 × 10-4
|
Glutathione transferase
|
|
YEL017W
|
GTT3
|
-2.2
|
6.72 × 10-4
|
Protein with a possible role in glutathione metabolism
|
|
YGR286C
|
BIO2
|
-3.0
|
9.79 × 10-4
|
Biotin synthase
|
|
YJL212C
|
OPT1
|
-2.5
|
1.8 × 10-4
|
Peptide transporter/glutathione transporter
|
|
YLL057C
|
JLP1
|
13.5
|
6.93 × 10-4
|
Fe(II)-dependent sulfonate/α-ketoglutarate dioxygenase
|
|
YLR043C
|
TRX1
|
-2.1
|
6.95 × 10-5
|
Cytoplasmic thioredoxin
|
|
d. Sulfur uptake
|
|
YBR294W
|
SUL1
|
-5.53
|
4.64 × 10-5
|
Sulfate uptake (transporter)
|
|
YLR092W
|
SUL2
|
-2.75
|
1.89 × 10-4
|
High affinity sulfate permease
|
