Skip to main content

Table 6 Pterostilbene-responsive genes involved in sulfur metabolism and/or assimilation

From: Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol

Accession Gene Ratio p-value Gene Description
a. Methionine metabolism
   YJR137C ECM17 -2.5 2.48 × 10-5 Sulfite reductase beta subunit
   YKR069W MET1 -3.1 3.88 × 10-4 AdoMet-dependent uroporphyrinogen III transmethylase
   YJR010W MET3 -3.8 3.5 × 10-4 ATP sulfurylase
   YER091C MET6 -2.4 8.83 × 10-5 Cobalamin-independent methionine synthase
   YFR030W MET10 -2.1 1.5 × 10-3 Sulfite reductase alpha subunit
   YGL125W MET13 -3.6 1.46 × 10-4 Methylenetetrahydrofolate reductase
   YKL001C MET14 -3.1 1.12 × 10-3 Adenylylsulfate kinase
   YPR167C MET16 -2.0 7.56 × 10-4 3'-phosphoadenylylsulfate reductase
   YOL064C MET22 -2.5 1.68 × 10-4 Bisphosphate-3'-nucleotidase,
   YLL062C MHT1 -3.4 6.69 × 10-4 S-methylmethionine-homocysteine methyltransferase
   YLR180W SAM1 -2.1 6.39 × 10-5 S-adenosylmethionine synthetase
b. Sulfur and aspartate family amino acid metabolic processes (in addition to a)
   YNL103W MET4 3.0 4.01 × 10-4 Leucine zipper transcriptional activator
   YPL038W MET31 2.2 2.45 × 10-3 Transcriptional regulator highly homologous to Met32p
   YJR130C STR2 2.3 2.97 × 10-3 Cystathionine gamma-synthase
   YGL184C STR3 -3.6 4.1 × 10-3 Cystathionine beta-lyase
   YJR060W CBF1 -3.0 1.11 × 10-3 Basic helix-loop-helix protein
   YHR025W THR1 -2.2 2.05 × 10-4 Homoserine kinase
c. All other genes affected under the term "sulfur metabolism"
   YLL060C GTT2 2.5 8.23 × 10-4 Glutathione transferase
   YEL017W GTT3 -2.2 6.72 × 10-4 Protein with a possible role in glutathione metabolism
   YGR286C BIO2 -3.0 9.79 × 10-4 Biotin synthase
   YJL212C OPT1 -2.5 1.8 × 10-4 Peptide transporter/glutathione transporter
   YLL057C JLP1 13.5 6.93 × 10-4 Fe(II)-dependent sulfonate/α-ketoglutarate dioxygenase
   YLR043C TRX1 -2.1 6.95 × 10-5 Cytoplasmic thioredoxin
d. Sulfur uptake
   YBR294W SUL1 -5.53 4.64 × 10-5 Sulfate uptake (transporter)
   YLR092W SUL2 -2.75 1.89 × 10-4 High affinity sulfate permease