Table 2 Genes identified as up-regulated response to antigen stimulation in previous studies with mycobacterial antigens.
Genbank | Symbol | *Fold PPD | *Fold BCG | *BCG over PPD | Cell type | Stimulus | Reference |
|---|---|---|---|---|---|---|---|
NM_000600 | IL-6 | 67.97 | 83.42 | 1.23 | Mφ1, Mφ, DC | M.tb, BCG | Chaussabel et. al. 2003 Verrek et. al. 2006 Begum et. al. 2004 |
NM_000576 | IL-1 β | 17.34 | 15.10 | 0.87 | Mφ1, Mφ, DC, Guinea-pig splenocytes | M.tb, BCG, PPD | Chaussabel et. al. 2003 Verrek et. al. 2006 Begum et. al. 2004 Khajoee et. al. 2006 Tree et. al. 2006 |
NM_001511 | GRO-1, CXCL1 | 27.12 | 16.89 | 0.62 | Mφ1, Mφ, DC | M.tb, BCG | Chaussabel et. al. 2003 Khajoee et. al. 2006 |
NM_002421 | MMP1 | 7.21 | 17.18 | 2.38 | Mφ1, Mφ, DC | M.tb, BCG | Chaussabel et. al. 2003 |
NM_002089 | GRO-2, CXCL2, MIP-2A | 19.24 | 24.10 | 1.25 | Mφ1, Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_002090 | GRO-3, CXCL3 | 15.94 | 9.91 | 0.62 | Mφ1 | M.tb | Chaussabel et. al. 2003 |
NM_000594 | TNF-α | 4.86 | 9.49 | 1.95 | Mφ1, Mφ, DC | M.tb, BCG | Chaussabel et. al. 2003 Verrek et. al. 2006 Begum et. al. 2004 |
NM_000963 | PTGS2, COX2 | 10.35 | 13.17 | 1.27 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_002984 | MIP-1β, CCL4 | 4.19 | 5.47 | 1.31 | Mφ1, Mφ, DC | M.tb | Chaussabel et. al. 2003 Verrek et. al. 2006 Cliff et al. 2004 |
NM_007115 | TNFAIP6. | 9.10 | 7.12 | 0.78 | Mφ, DC | M.tb, BCG | Chaussabel et. al. 2003 Khajoee et. al. 2006 |
NM_000584 | IL-8 | 3.62 | 3.60 | 0.99 | Mφ1, Mφ, DC, Guinea-pig splenocytes, CD4+ | M.tb, BCG, PPD | Chaussabel et. al. 2003 Verrek et. al. 2006 Khajoee et. al. 2006 Tree et. al. 2006 Cliff et al. 2004 |
NM_139266 | STAT-1 | 2.41 | 4.52 | 1.88 | Mφ, DC Mφ | M.tb PPD | Chaussabel et. al. 2003, Begum et. al. 2004 |
NM_015714 | GOS-2 | 4.36 | 4.26 | 0.98 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_004184 | WARS | 1.52 | 2.29 | 1.51 | Mφ, DC Guinea-pig splenocytes | M.tb PPD | Chaussabel et. al. 2003 Tree et. al. 2006 |
NM_000595 | LTA | 2.31 | 2.28 | 0.99 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_001955 | EDN1 | 1.93 | 3.41 | 1.77 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_001565 | IP-10, CXCL10 | 2.28 | 3.56 | 1.56 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_002462 | MX1 | 1.26 | 1.59 | 1.26 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_002164 | INDO | 3.01 | 2.42 | 0.80 | Mφ, DC |  | Chaussabel et. al. 2003 |
NM_002460 | IRF4 | 1.56 | 1.89 | 1.21 | Mφ, DC | M.tb | Chaussabel et. al. 2003 |
NM_002990 | MDC, CCL22 | 3.53 | 3.12 | 0.88 | Mφ1 | M.tb | Verrek et. al. 2006 |
NM_005746 | PBEF | 3.36 | 2.37 | 0.71 | Mφ | BCG | Begum et. al. 2004 |
NM_002187 | IL-12p40 | 1.98 | 2.66 | 1.35 | Mφ | BCG | Begum et. al. 2004 |
NM_004591 | CCL20, MIP3A | 24.49 | 37.96 | 1.55 | Mφ2 | BCG | Khajoee et. al. 2006 |
NM_000636 | SOD2 | 4.25 | 3.61 | 0.85 | Mφ1 | BCG | Khajoee et. al. 2006 |
NM_004049 | BCL2A1 | 2.75 | 2.55 | 0.93 | Mφ1 CD8+ | BCG, M.tb | Khajoee et. al. 2006 Cliff et. al. 2004 |
NM_002053 | GBP1 | 2.31 | 5.25 | 2.28 | Bovine PBMC | PPD | Meade et. al. 2006 |
NM_000758 | GM-CSF | 36.79 | 77.65 | 2.11 | Guinea-pig splenocytes | PPD | Tree et. al. 2006 |
NM_000575 | IL-1alpha | 21.60 | 22.38 | 1.04 | Guinea-pig splenocytes | PPD | Tree et. al. 2006 |
NM_003745 | SOCS-1 | 1.65 | 2.37 | 1.44 | CD8+ | M.tb | Cliff et al. 2004 |
NM_172219 | CSF3, G-CSF | 2.93 | 9.17 | 3.13 | CD8+ | M.tb | Cliff et al. 2004 |