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Table 2 Proportion of significantly changed genes by functional category.

From: Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data

Gene Ontology (GO)

Observed %

Expected %

p value

Extracellular region (5576)

16.3

5.3

0.00698

Extracellular matrix (31012)

13.95

2.4

0.000503

Intermediate filament cytoskeleton (45111)

6.977

0.53

0.00197

Intermediate filament (5882)

6.977

0.58

0.00197

Muscle development (7517)

6.977

1.16

0.0135

Transporter activity (5215)

23.26

12.06

0.0291

Structural molecule activity (5198)

20.93

5.424

0.000414

Extracellular matrix structural constituents (5210)

9.302

0.675

0.000198

Oxidoreductase activity acting on paired donors (16705)

6.977

0.631

0.0025

  1. Note: This refers to primary pterygium versus control. Only functional categories which represent at least 5% of the significantly changed genes are shown. The numbers in the brackets represent the GO category ID.