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Table 5 Gene microarray data corresponding to detected tear proteins.

From: Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data

Name of gene corresponding to tear protein Genbank Accession No of fold change p value
A. Genes significantly regulated in pterygium    
Prolactin-induced protein I NM_002652 2.149 0.000213
S100A8 (Calgranulin A) NM_002964 1.74 0.0000082
Defensin alpha A1 U73945 1.506 0.0149
S100 A9 NM_002965 1.442 0.00204
Hepatocellular carcinoma associated protein (PIGR) NM_002644 1.371 0.0299
Vimentin AI922599 1.278 0.0324
Beta-2 microglobulin NM_004048 1.188 0.0378
Cathepsin G NM_001911 1.141 0.00984
S100 A12 NM_005621 1.122 0.0268
Clusterin (Apolipoprotein J) AI982754 1.08 0.0287
Vitamin D binding protein NM_000583 1.052 0.0437
Cystatin SN NM_001898 0.946 0.0121
Histone 1b NM_005322 0.941 0.00456
Orosomucoid 1 (alpha 1 acid glycoprotein) NM_000607 0.94 0.0027
Anti-thrombin III D29832 0.937 0.000451
Beta actin X00351 0.888 0.0263
Proline rich Peptide NM_025263 0.864 0.00355
Ribonuclease 4 NM_002937 0.725 0.000675
Alpha-1-antitrypsin (SERPINA1) NM_000295 0.72 0.0399
Ceruloplasmin (ferroxidase) NM_000096 0.637 0.000375
Complement C3 NM_000064 0.607 0.00443
Lipophilin C (SCGB2A1) NM_002407 0.402 0.000045
B. Genes not significantly regulated in pterygium    
IGHM protein L23517 0.89 0.0511
Lipophilin A NM_006552 0.955 0.073
Zn-alpha2-glycoprotein D90427 1.223 0.0788
Apolipoprotein A-I NM_000039 0.934 0.0874
Immunoglobulin kappa light M63438 0.559 0.0878
Mucin 7 L13283 1.023 0.0895
Lipocalin 1 NM_002297 0.949 0.135
Alpha-fibrinogen NM_021871 1.038 0.261
Transferrin A1073407 0.97 0.319
Proline rich 4 (lacrimal) NM_007244 0.959 0.32
Nasopharyngeal carcinoma associated proline rich protein 4 NM_007244 0.959 0.32
Lactoferrin NM_002343 1.068 0.366
Complement Factor-B AF349679 1.048 0.386
Immunoglobulin J chain AV733266 0.707 0.398
cystatin SA NM_001322 0.977 0.415
Apolipoprotein A-IV NM_000482 0.977 0.442
Transthyretin AH62690 1.024 0.493
Lysozyme NM_020426 0.982 0.527
Complement factor H X04697 0.956 0.542
Annexin I NM_000700 0.959 0.583
Secretary leukocyte protease inhibitor NM_003064 0.944 0.592
Proline rich protein 5 NM_012390 1.145 0.597
Coagulation factor H (thrombin) NM_000506 0.979 0.6
Neutrophil elastase NM_001972 0.99 0.68
Apolipoprotein H NM_000042 1.013 0.691
Hemopexin BC005395 1.013 0.7
Albumin AF116645 1.007 0.8
Haptoglobin NM_005143 1.005 0.836
Basic proline rich protein X07882 1.004 0.905
  1. Note: the study did not have expression data for the genes corresponding to the following tear proteins: defensins HNP-2 and HNP-3, lacritin and DMBT1.