Bicluster of microRNA expression. Hierarchical clustering was carried out using correlation distance as the distance metric and average linkage between clusters to perform the analysis. This is a non-supervised method to illustrate potential relationships between the miRNA expression profiles from different samples. Hierarchical clustering was carried out for all samples and miRNA. The top of the figure indicates relationships between the various samples. The left-hand side shows the relationships between the miRNA identified on the right-hand side. The color of each cell reflects fold-change of the observed hybridization intensity relative to average hybridization intensity across all samples. Saturated green cells represent decrease in hybridization intensity, whereas saturated red cells represent an increase.