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Table 1 Representative list of genes changed between hypoxia and normoxia including number of miRNAs predicted to have target sites in each gene (p ≤ 0.001).

From: Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis

Symbol

Gene Description

Number of miRNAs as predicted by miRBase

Fold Change

ALDOC

fructose-bisphosphate aldolase C

35

76.01

ANGPTL4

angiopoietin-like 4

69

74.01

PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

14

20.63

HIG2

hypoxia-inducible protein 2

34

16.55

EGLN3

egl nine homolog 3 (C. elegans)

13

13.80

CA9

carbonic anhydrase IX

15

12.04

VEGF

vascular endothelial growth factor

15

9.68

EGR1

Early growth response 1

15

0.02

DDX28

DEAD (Asp-Glu-Ala-Asp) box polypeptide 28

7

0.03

NOX1

NADPH oxidase 1

8

0.03

CFTR

cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)

13

0.16

DDX52

DEAD (Asp-Glu-Ala-Asp) box polypeptide 52

6

0.18

DDX27

DEAD (Asp-Glu-Ala-Asp) box polypeptide 27

8

0.26

FPGT

fucose-1-phosphate guanylyltransferase

34

0.31

  1. Examples of genes relevant to oxygen deprivation or related areas are shown.