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Figure 7 | BMC Medical Genomics

Figure 7

From: The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

Figure 7

AM trascriptome in cancer. Panel A. Expression matrix of protein-encoding AM genes in cancer. Up regulated genes are depicted in red, down regulated genes in green. Each row represents the colour coded expression of a specific gene in the indicated cancer models; the columns represent the colour coded AM profiles of each cancer model. The dendrogram above the matrix represents the clusters of the tumours. Panel B. Percentage of dysregulated AM genes in cancer. Panel C. Matrix of identity profile of AM dysregulation in cancer, based on number of the same dysregulated genes for each couple of models normalized for their average number of altered genes.

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