AM GENES | FAMILY | PATHWAY | FUNCTION |
---|---|---|---|
APAF1 | Â | p53 Pathway, Apoptosome | PRO |
BAD | Â | Apoptotic Mitochondrial Pathway | PRO |
BAK1 | BCL-2 RELATED | Apoptotic Mitochondrial Pathway | PRO |
BAX | BCL-2 RELATED | Apoptotic Mitochondrial Pathway, p53 Pathway | PRO |
BCL2L1 | BCL-2 RELATED | Apoptotic Mitochondrial Pathway | PRO* |
BID | BCL-2 RELATED | Apoptotic Mitochondrial Pathway | PRO |
CARD12 | NALP | Caspase Cascade | PRO |
CARD4 | NALP | Caspase Cascade | PRO |
CARD8 | NALP | Caspase Cascade | PRO |
CASP10 | CASPASE | Caspase Cascade | PRO |
CASP3 | CASPASE | Caspase Cascade | PRO |
CASP6 | CASPASE | Caspase Cascade | PRO |
CASP7 | CASPASE | Caspase Cascade | PRO |
CASP8 | CASPASE | Caspase Cascade | PRO |
CASP9 | CASPASE | Caspase Cascade, Apoptosome | PRO |
CFLAR | CASPASE | FAS Signaling Pathway | PRO* |
CHUK | SER/THR KINASE | AKT Signaling Pathway, Induction of Apoptosis through DR3 and DR4/5 Death Receptors | PRO |
CYCS | Â | Caspase Cascade, Apoptosome | PRO |
DAP | Â | IFN-Gamma-Induced Cell Death | PRO |
DAP3 | Â | IFN-Gamma-Induced Cell Death, FAS Signaling Pathway, SODD/TNFR1 Signaling Pathway | PRO |
DAPK1 | Â | IFN-Gamma-Induced Cell Death | PRO |
DAXX | Â | FAS Signaling Pathway | PRO |
DFFA | Â | Apoptotic DNA Fragmentation and Tissue Homeostasis | PRO |
DFFB | Â | Apoptotic DNA Fragmentation and Tissue Homeostasis | PRO |
FADD | Â | FAS Signaling Pathway | PRO |
FAS | TNF RECEPTOR | FAS Signaling Pathway | PRO* |
FASLG | TNF | FAS Signaling Pathway | PRO |
HRK | Â | Apoptotic Mitochondrial Pathway | PRO |
IL1A | INTERLEUKIN 1 CYTOKINE | NF-kB Signaling Pathway | PRO* |
IL1R1 | INTERLEUKIN 1 RECEPTOR | NF-kB Signaling Pathway | PRO* |
MCL1 | BCL-2 RELATED | Apoptotic Mitochondrial Pathway | PRO* |
NALP1 | NALP | FAS Signaling Pathway | PRO |
NFKBIA | Â | AKT Signaling Pathway, Induction of Apoptosis through DR3 and DR4/5 Death Receptors, NF-kB Signaling Pathway | PRO |
RIPK1 | SER/THR KINASE | NF-kB Signaling Pathway, Induction of Apoptosis through DR3 and DR4/5 Death Receptors | PRO |
TNF | TNF | SODD/TNFR1 Signaling Pathway | PRO* |
TNFRSF10A | TNF RECEPTOR | Induction of Apoptosis through DR3 and DR4/5 Death Receptors, Natural Killer Cell Mediated Cytotoxicity | PRO |
TNFRSF10B | TNF RECEPTOR | p53 Pathway, Natural Killer Cell Mediated Cytotoxicity | PRO |
TNFRSF1A | TNF RECEPTOR | SODD/TNFR1 Signaling Pathway | PRO |
TNFSF10 | TNF | Induction of Apoptosis through DR3 and DR4/5 Death Receptors | PRO |
TP53 | TP53-RELATED | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, | PRO |
TRADD | Â | Induction of Apoptosis through DR3 and DR4/5 Death Receptors | PRO |
TRAF2 | TRAF | Induction of Apoptosis through DR3 and DR4/5 Death Receptors | PRO* |