Table 2 Anti AM core genes
AM GENES | FAMILY | PATHWAY | FUNCTION |
|---|---|---|---|
AKT1 | SER/THR KINASE | FAS Sgnaling Pathway | ANTI |
BAG1 | BCL2-ASSOCIATED ATHANOGENE | SODD/TNFR1 Signaling Pathway | ANTI |
BAG3 | BCL2-ASSOCIATED ATHANOGENE | SODD/TNFR1 Signaling Pathway | ANTI |
BAG4 | BCL2-ASSOCIATED ATHANOGENE | SODD/TNFR1 Signaling Pathway | ANTI |
BCL2 | BCL-2 RELATED | Apoptotic Mitochondrial Pathway, p53 Pathway | ANTI |
BCL2L1 | BCL-2 RELATED | Apoptotic Mitochondrial Pathway | ANTI* |
BIRC2 | BIRC | Apoptotic Mitochondrial Pathway, Caspase Cascade | ANTI |
BIRC3 | BIRC | Apoptotic Mitochondrial Pathway, Caspase Cascade, SODD/TNFR1 Signaling Pathway | ANTI |
BIRC4 | BIRC | Apoptotic Mitochondrial Pathway, Caspase Cascade, B Cell Survival Pathway | ANTI |
BIRC5 | BIRC | B Cell Survival Pathway | ANTI |
CFLAR | CASPASE | FAS Signaling Pathway | ANTI* |
FAS | TNF RECEPTOR | FAS Signaling Pathway | ANTI* |
IL1A | INTERLEUKIN 1 CYTOKINE | NF-kB Signaling Pathway | ANTI* |
IL1R1 | INTERLEUKIN 1 RECEPTOR | NF-kB Signaling Pathway | ANTI* |
MAP3K14 | SER/THR KINASE | NF-kB Signaling Pathway, Induction of Apoptosis through DR3 and DR4/5 Death Receptors | ANTI |
MCL1 | BCL-2 RELATED | Apoptotic Mitochondrial Pathway | ANTI* |
MYD88 | Â | NF-kB Signaling Pathway | ANTI |
NFKB1 | Â | AKT Signaling Pathway, Induction of Apoptosis through DR3 and DR4/5 Death Receptors, NF-kB Signaling Pathway | ANTI |
NFKB2 | Â | AKT Signaling Pathway, Induction of Apoptosis through DR3 and DR4/5 Death Receptors, NF-kB Signaling Pathway | ANTI |
RELA | Â | NF-kB Signaling Pathway | ANTI |
TNF | TNF | SODD/TNFR1 Signaling Pathway | ANTI* |
TNFRSF10C | TNF RECEPTOR | Natural Killer Cell Mediated Cytotoxicity | ANTI |
TNFRSF10D | TNF RECEPTOR | Natural Killer Cell Mediated Cytotoxicity | ANTI |
TRAF2 | TRAF | Induction of Apoptosis through DR3 and DR4/5 Death Receptors | ANTI* |