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Table 3 AM genes mutated in specific cancers

From: The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

Breast ATM – BIRC6 – BRAF – BRCA2 – CDKN2A – CHUK – DAPK1 – HRAS – HUWE1 – NFKB1 – NFKBIA – PTPN13 – RB1 – STAT1 – TP53
Colon BRAF – BRCA2 – CDKN2A – RB1 – SRC – TP53
Kidney ATM – AVEN – BRAF – CASP3 – CASP9 – CDKN2A – CUL3 – HRAS – MAPK8 – RB1 – TP53
Leukemia ABL1 – BRAF – CDKN2A – HRAS – RB1 – TP53
Liver BRAF – BRCA2 – CDKN2A – RB1 – TP53
Lung AATK – ABL1 – APAF1 – ATM – BCL2L13 – BIRC4 – BIRC6 – BIRC8 – BNIP3 – BRAF – BRCA2 – CARD6 – CASP14 – CASP4 – CASP5 – CDKN2A – CHUK – CREBBP – CUL4B – CYCS – DAPK3 – FASTK – HRAS – IRAK3 – MAP3K14 – MYBL2 – NTRK1 – P53AIP1 – PAX7 – PDCD5 – RAF1 – RB1 – RET – SGK – SGK3 – STK17B – STK3 – TGFBR2 – TNFRSF9 – TP53
Neuroblastoma BRAF – CDKN2A – TP53
Ovary AATK – BRAF – BRCA2 – CDKN2A – DAPK3 – MAP3K14 – NTRK1 – RAF1 – RB1 – RET – STK3 – TP53
Pancreas BIRC6 – BRAF – CDKN2A – FAF1 – TP53
Prostate BRAF – CDKN2A – HRAS – RB1 – TP53
Skin ABL1 – BAX – BCL2L13 – BCL2L14 – BIRC3 – BIRC6 – BNIP3 – BRAF – BRCA2 – CARD14 – CARD6 – CASP10 – CASP4 – CASP8 – CD40 – CDC2L1 – CDKN2A – CORO1C – CREBBP – CUL4A – DAXX – E2F6 – ENC1 – HIPK2 – HRAS – IL4R – MAPK7 – MYCN – PDCD4 – PDCD6IP – RB1 – RIPK1 – TNF – TNFRSF1A – TNFRSF8 – TNFRSF9 – TNFSF10 – TNFSF13 – TP53 – TP73L – TRAF2
Stomach AATK – ATM – BRAF – CDKN2A – FASTK – HRAS – JAK1 – NTRK1 – RB1 – SGK – TGFBR2 – TP53
Thyroid BRAF – CDKN2A – HRAS – RET