Skip to main content

Table 4 Methylations of AM genes associated to cancer

From: The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

GENE

Breast

Colon

Kidney

Leukaemia

Liver

Lung

NB

Ovary

Pancreas

Prostate

Skin

Stomach

Thyroid

ABL1

   

47

         

APAF1

  

98

35

         

ATM

 

10

           

BCL2

18

22

       

52

   

BCL2L10

           

80

 

BDNF

           

80

 

BIRC4

 

75

         

75

 

BNIP3

 

66

 

16

     

80

 

49

 

BRCA2

       

5

     

CASP8

    

100

 

37

      

CD44

      

20

  

33

   

CDKN1A

   

41

     

8

   

CFLAR

      

5

      

DAPK1

55

47

32

16

7

34

16

67

14

16

19

51

24

DIABLO

   

25

         

DUSP6

        

42

    

FAS

 

40

       

13

   

FOXE1

        

70

    

GADD45A

60

            

GADD45G

 

20

 

33

20

40

     

11

 

GPR37

   

72

         

GSK3B

 

2

           

HRAS

100

            

HRK

 

14

         

17

 

IGFBP3

18

 

38

  

70

 

43

  

32

71

 

PYCARD

30

25

 

8

36

46

31

19

 

52

63

5

 

RB1

17

  

14

25

19

21

  

8

5

42

 

TGFBR2

30

        

100

   

TNFRSF10A

      

48

      

TNFRSF10C

70

  

26

 

23

25

31

 

65

   

TNFRSF10D

74

    

28

31

  

25

   

TP53

12

   

13

        

TP73

50

61

 

20

22

 

29

 

14

  

29

 
  1. Numeric values correspond to the mean of methylation degree (% of sample where methylation was detected in primary samples, according to Pubmeth).