Identification of microbial DNA in human cancer

BMC Medical Genomics

Table 1 Probability of detecting microbial virtual tags using DK-MICROBE

Average microbial tag number per cell	Probability of detecting at least one virtual tag given the number of DK tags sequenced (%)^
	50,000	100,000	200,000	500,000	1,000,000	2,000,000
2	4.5	8.7	16.7	36.7	59.9	83.9
20	36.7	59.9	83.9	99	100	100
200	99	100	100	100	100	100

^The probability of detecting at least one microbial tag by sequencing r tags is 1 minus the probability of detecting none of the microbial tags among m human tags and n microbial tags (1-[m/(m+n)]^r), where m = 2,188,960 (total number of human virtual tags in a diploid genome).

ISSN: 1755-8794