Functional group | Gene set name | No. of related sets | No of members in gene set (range) | FDR qvalue (range) |
---|---|---|---|---|
Vesicle trafficking | Membrane fusion | 2 | 27–52 | 0.022–0.026 |
 | Vesicle transport | 9 | 16–348 | 0.002–0.149 |
 | Vesicle docking during exocytosis | 1 | 21 | 0.141 |
Transcription/translation | Ribosome function | 4 | 69–89 | 0.042–0.179 |
 | mRNA processing | 5 | 157–452 | 0.056–0.166 |
 | Transcription from RNA pol III promoter | 1 | 25 | 0.089 |
 | mRNA catabolism | 2 | 17–23 | 0.027–0.125 |
 | translation | 3 | 30–157 | 0.012–0.062 |
Protein transport/metabolism | Protein transport | 9 | 17–294 | 0.012–0.129 |
 | Ubiquination/proteolysis | 11 | 133–448 | 0.013–0.024 |
 | Protein folding | 1 | 195 | 0.003 |
 | Carboxylic acid metabolism | 7 | 17–410 | 0.087–0.195 |
 | Aspartate family amino acid metabolism | 1 | 18 | 0.016 |
 | Amine metabolism | 2 | 55–57 | 0.142–0.152 |
Electron transport chain | Coenzyme metabolism | 4 | 85–159 | 0.007–0.029 |
 | Nucleotide metabolism | 16 | 53–178 | 0.014–0.126 |
 | ATP metabolism | 9 | 36–490 | 0.012–0.192 |
 | Oxidative phosphorylation | 4 | 21–63 | <0.001 |
 | Electron transport | 1 | 289 | 0.022 |
 | Mitochondrial membrane | 2 | 19–21 | 0.027–0.149 |
Glycolysis | Aerobic respiration | 7 | 22–32 | 0.005–0.016 |
 | Glucose metabolism | 13 | 20–138 | 0.005–0.079 |
Oxidative stress | Response to oxidative stress | 2 | 44–63 | 0.069–0.164 |
 | Peroxisome organization and biogenesis | 1 | 17 | 0.164 |
Cell cycle | Mitotic cell cycle | 5 | 17–60 | 0.077–0.144 |
 | Induction of apoptosis by intracellular signals | 1 | 20 | 0.067 |
Lipid metabolism | Sphingomyelin synthesis | 3 | 17–41 | 0.035–0.187 |
 | Lipid modification | 2 | 15–19 | 0.032–0.041 |
 | Phospholipid metabolism | 6 | 54–427 | 0.012–0.054 |
 | Lipoprotein metabolism | 3 | 29–42 | 0.027–0.069 |
 | Glycerolipid metabolism | 6 | 19–39 | 0.013–0.180 |
Others | Iron compound metabolism | 6 | 15–52 | 0.002–0.053 |
 | Autophagy | 1 | 16 | 0.062 |
 | Polysaccharide biosynthesis | 1 | 18 | 0.120 |
 | Biopolymer biosynthesis | 1 | 18 | 0.128 |
 | Telomere maintenance | 1 | 21 | 0.132 |
 | Respiratory gaseous exchange | 1 | 17 | 0.188 |
 | Regulation of Wnt receptor signalling | 1 | 15 | 0.188 |
 | Vitamin metabolism | 1 | 48 | 0.188 |