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Table 2 Significantly different chromosomal alterations between hrHPV+ and hrHPV- carcinomas.

From: Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck

      HPV+ (HNSCC; CxSCC) HPV-
chromosome Start (Mb) End (Mb) Cytoband FDR % loss % gain % amp % loss %gain %amp
1 1.08 58.69 1p36.33-p32.2 0.08 0.0 26.7 (15.6; 40.0) 0.0 14.6 5.8 0.0
1 109.78 117.23 1p13.3-p13.1 0.04 0.0 13.6 (16.7; 10.0) 0.0 17.8 0.0 0.0
2 96.17 97.68 2q11.2 0.08 4.5 (0.0; 10.1) 0.0 0.0 0.0 20.0 0.0
2 165.89 180.53 2q24.3-q31.3 0.06 9.1 (8.3; 10.0) 0.0 0.0 0.0 18.9 0.0
3 0.28 86.18 3p26.3-p12.1 0.00 17.8 (20.5; 14.6) 9.4 (3.8; 16.2) 0.0 86.2 0.5 0.0
5 51.16 180.57 5q11.2-q35.3 0.00 8.6 (7.5; 10.0) 9.1 (8.3; 10.0) 0.0 61.0 0.3 0.0
7 9.95 25.67 7p21.3-p15.2 0.05 13.6 (16.7; 10.0) 0.0 0.0 3.3 21.7 0.0
7 65.52 116.45 7q11.21-q31.2 0.03 4.5 (0.0; 10.0) 0.3 (0.6; 0.0) 0.0 4.1 32.1 2.8
8 0.38 34.51 8p23.3-p12 0.02 6.8 (12.5; 0.0) 17.3 (31.7; 0.0) 0.0 48.7 12.0 0.0
8 75.65 93.93 8q21.11-q22.1 0.06 0.0 22.7 (41.7; 0.0) 0.0 3.3 57.8 0.0
8 114.72 145.68 8q23.3-q24.3 0.05 0.3 (0.0; 0.7) 34.4 (55.4; 9.3) 0.0 0.5 70.2 2.1
11 69.18 70.31 11q13.3-q13.4 0.04 11.4 (12.5; 10.0) 13.6 (0.0; 30.0) 4.5 (8.3; 0.0) 10.0 15.0 41.7
13 55.72 71.49 13q21.1-q21.33 0.06 66.7 (64.8; 68.9) 0.0 0.0 33.0 7.0 2.2
14 47.08 61.97 14q21.3-q23.2 0.08 11.4 (12.5; 10.0) 2.3 (0.0; 5.0) 0.0 8.3 28.3 0.0
14 79.43 86.91 14q31.1-q31.3 0.09 18.2 (25.0; 10.0) 9.1 (0.0; 20.0) 0.0 6.7 33.3 0.0
18 28.34 75.62 18q12.1-q23 0.03 10.0 (8.3; 12.0) 18.2 (25.0; 10.0) 0.0 42.7 2.0 0.0
20 15.56 60.28 20p12.1-q13.33 0.06 1.5 (2.8; 0.0) 58.5 (41.7; 78.7) 0.0 6.2 24.0 0.0
21 14.68 46.85 21q11.2-q22.3 0.00 1.1 (0.0; 2.5) 25.0 (14.6; 37.5) 0.0 33.3 2.5 0.0
  1. hrHPV-specific alterations are printed in bold. Alterations specific for hrHPV-negative HNSCCs are italicised. Mb; Megabases, FDR; False Discovery Rate, amp; amplification
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