MiRNAs and conservation near the alternative mir-500 locus. Location and conservation of the proposed alternative mir-500 compared to the known mir-500 and nearby miRNA genes. Shown in black is the mature miR-500 sequence within the alternative precursor. The red blocks show currently known miRNA precursors, and the blue peaks show Phastcons conservation [52–54]. The mature miR-500 sequence is highly conserved in the alternative precursor. Figure generated via the UCSC genome browser .