5' and 3' miRNA end variation. a) The figure conceptually shows how the tiling of reads in a miRNA precursor produces variation in the 5'/3' ends and loop proximal/distal ends of observed miRNA (blue reads) and miRNA* (orange reads) sequences. Expression counts are shown next to each read. In the figure miR-22 reads from the BN sample is used as example. b+c) The 219 known mature miRNAs expressed with a minimum total count of 3 in our samples. b) The cumulative distribution of mean absolute deviations from the annotated mature miRNA end. c) The mean absolute deviation of the 5' end versus the 3' end for each of the 219 expressed mature miRNAs.