miRNA | BN | BC | Fold change |
---|
mir-200b | 22.8 (1) | 27122.2 (2325) | 1189.6 |
mir-200c | 45.5 (2) | 44072.2 (3778) | 968.6 |
mir-21 | 22.8 (1) | 15363.4 (1317) | 673.8 |
mir-378 | 68944.3 (3027) | 466.6 (40) | -147.8 |
let-7a | 2186.5 (96) | 50313.2 (4313) | 23.0 |
mir-320 | 136180.4 (5979) | 19376.4 (1661) | -7.0 |
mir-23a | 11319.9 (497) | 44748.8 (3836) | 4.0 |
mir-22 | 25646.3 (1126) | 7150.9 (613) | -3.6 |
- MiRNAs significantly differentially expressed in normal breast (BN) and breast cancer (BC) samples, with False Discovery Rate of 0.05. Columns show the miRNA id, the observed expression in BN and BC as parts-per-million (ppm) and raw read counts in parentheses, and the relative fold change. The ppm values were based on the total number of 19 – 24 nt long reads in each library. Five miRNAs were found to be overexpressed in BC compared to BN (positive fold change), while three were underexpressed (negative fold change).