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Table 2 SAM results

From: MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

Constant part

Phenotype

Phenotype

Translocation

Translocation

Variable part

Translocation

Translocation

Phenotype

Phenotype

Comparison ID

L1

L3

L2

L4

SAM comparisons

ALL/MLL(-) vs ALL/MLL(+)

AML/MLL(-) vs AML/MLL(+)

ALL/MLL(-) vs AML/MLL(-)

ALL/MLL(+) vs AML/MLL(+)

up/down ALL/MLL(-)

1013/740

 

1378/754

 

up/down AML/MLL(-)

 

155/555

754/1378

 

up/down ALL/MLL(+)

740/1013

  

379/601

up/down AML/MLL(+)

 

555/155

 

601/379

Total

1753

710

2132

980

(Common) Signature

379 Translocation specific

622 Phenotype specific

  1. SAM results for comparisons between considered subgroups. Translocation-specific signature was obtained by matching deregulated probe sets from L1 and L3 comparisons, phenotype-specific signature from L2 and L4 comparisons.