Skip to main content

Table 2 Intensities in cases and controls of the peaks most likely representing the previously reported proteins [24] in order of m/z

From: Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study

 

Breast cancer cases

(n = 47)

Healthy controls

(n = 48)

 

Mann-Whitney U test

ROC-curve

M/z

Median intensity

IQR

Median

intensity

IQR

Intensity in cases vs. controls

p-value

AUC

95%CI

4276

11.04

2.10 – 29.31

39.48

14.17 – 77.58

Decreased

<0.0001

0.716

0.61–0.82

4292

14.54

8.52 – 29.54

42.07

29.67 – 63.39

Decreased

<0.0001

0.770

0.67–0.87

8129

25.92

20.48 – 28.19

26.05

21.06 – 28.08

-

0.870

0.510

0.39–0.63

8941

31.27

24.07 – 44.88

73.47

48.69 – 86.72

Decreased

<0.0001

0.830

0.75–0.91

  1. M/z = Mass to Charge ratio, IQR = Inter-Quartile Range, ROC-curve = Receiver Operating Characteristic curve, AUC = Area Under the Curve, 95%CI = 95% Confidence Interval