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Table 4 The relationships between peak intensities and the presence of breast cancer before and after adjustment for sample characteristics and subject age

From: Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study

  n Crude OR (95%CI) Adjusted OR* (95%CI)
  cases controls   
M/z 4276     
   Low intensity 36 16 6.0 (2.0–18.2) 5.3 (1.7–17.0)
   Intermediate intensity 5 16 0.8 (0.2–3.3) 0.9 (0.2–3.7)
   High intensity 6 16 1.0 (referent) 1.0 (referent)
M/z 4292     
   Low intensity 38 16 7.6 (2.4–24.3) 6.4 (1.8–22.3)
   Intermediate intensity 4 16 0.8 (0.2–3.5) 0.7 (0.2–3.1)
   High intensity 5 16 1.0 (referent) 1.0 (referent)
M/z 8129     
   Low intensity 13 16 0.8 (0.3–2.3) 0.7 (0.2–2.0)
   Intermediate intensity 19 17 1.1 (0.4–2.9) 1.0 (0.4–2.8)
   High intensity 15 15 1.0 (referent) 1.0 (referent)
M/z 8941     
   Low intensity 39 16 13.0 (3.3–50.8) 13.3 (3.2–55.0)
   Intermediate intensity 5 16 1.7 (0.3–8.2) 1.8 (0.4–9.1)
   High intensity 3 16 1.0 (referent) 1.0 (referent)
  1. * OR's (odds ratios) with 95%CI (95% Confidence Interval) were adjusted for the following variables; day of preparation (day 1 or day 2), age (continuous) and storage duration (continuous).
  2. M/z = Mass to Charge ratio, Tertiles of the intensities per peak were determined in the controls, separately for day of preparation, applied to cases prepared on the same day and afterwards combined in three categories.