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Table 4 The relationships between peak intensities and the presence of breast cancer before and after adjustment for sample characteristics and subject age

From: Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study

 

n

Crude OR (95%CI)

Adjusted OR* (95%CI)

 

cases

controls

  

M/z 4276

    

   Low intensity

36

16

6.0 (2.0–18.2)

5.3 (1.7–17.0)

   Intermediate intensity

5

16

0.8 (0.2–3.3)

0.9 (0.2–3.7)

   High intensity

6

16

1.0 (referent)

1.0 (referent)

M/z 4292

    

   Low intensity

38

16

7.6 (2.4–24.3)

6.4 (1.8–22.3)

   Intermediate intensity

4

16

0.8 (0.2–3.5)

0.7 (0.2–3.1)

   High intensity

5

16

1.0 (referent)

1.0 (referent)

M/z 8129

    

   Low intensity

13

16

0.8 (0.3–2.3)

0.7 (0.2–2.0)

   Intermediate intensity

19

17

1.1 (0.4–2.9)

1.0 (0.4–2.8)

   High intensity

15

15

1.0 (referent)

1.0 (referent)

M/z 8941

    

   Low intensity

39

16

13.0 (3.3–50.8)

13.3 (3.2–55.0)

   Intermediate intensity

5

16

1.7 (0.3–8.2)

1.8 (0.4–9.1)

   High intensity

3

16

1.0 (referent)

1.0 (referent)

  1. * OR's (odds ratios) with 95%CI (95% Confidence Interval) were adjusted for the following variables; day of preparation (day 1 or day 2), age (continuous) and storage duration (continuous).
  2. M/z = Mass to Charge ratio, Tertiles of the intensities per peak were determined in the controls, separately for day of preparation, applied to cases prepared on the same day and afterwards combined in three categories.
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BMC Medical Genomics

ISSN: 1755-8794

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