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Table 7 Description of the peaks found in the different studies

From: Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study

  

Protein 1

Protein 2

Protein 3

Li et al. (2002) [3]

kDa

4.3 ↓

8.1 ↑

8.9 ↑

 

AUC

0.846

0.795

0.934

 

p-value

-

-

-

Mathelin et al. (2005) [2]

M/z

4286 ↓

4302 ↓

8129 -

8919 ↑

8961 ↑

 

AUC

-

-

-

-

-

 

p-value#

<0.000

<0.001

0.51

<0.02

<0.001

Li et al. (2005)

Da

± 4300* ↑

8116 ↑

8926 ↑

Validation study [4]

AUC

-

0.65

0.71

 

p-value

-

-

-

Current study

M/z

4276 ↓

4292 ↓

8129 -

8941 ↓

 

AUC

0.716

0.770

0.510

0.830

 

p-value

<0.0001

<0.0001

0.870

<0.0001

  1. ↓ = Decreased intensity in cases compared to controls, ↑ = Increased intenstiy in cases compared to controls.
  2. M/z = Mass to Charge ratio, * Exact mass not reported, # Test used not reported, Mann-Whitney U Test