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Table 3 Significantly altered genes in functional categories

From: Novel transcriptional profile in wrist muscles from cerebral palsy patients

   P-Values    P-Values
GENE Ratio MAS5 RMA GCRMA GENE Ratio MAS5 RMA GCRMA
Neuromuscular Junction Muscle Contraction and Structure
KCNN3 12.98 0.013 0.011 0.018 MYH1 8.57 0.001 0.001 0.000
COL4A3 2.89 0.043 0.014 0.019 MYH4 4.33 0.001 0.002 0.015
LAMB2 1.74 0.042 0.018 0.015 NEB 2.54 0.015 0.008 0.013
Excitation Contraction Coupling MYBPC2 2.16 0.027 0.004 0.004
PVALB 62.60 0.001 0.004 0.001 DMD 2.11 0.023 0.020 0.027
ATP2B2 2.60 0.033 0.023 0.021 LDB3 1.93 0.030 0.015 0.015
TRDN 2.38 0.028 0.019 0.017 Metabolism/Mitochondria Related
ATP2C1 2.30 0.046 0.047 0.041 WARS 0.64 0.044 0.040 0.019
PDE4DIP 2.10 0.005 0.003 0.004 CAV1 0.64 0.037 0.013 0.017
CALM1 1.70 0.005 0.004 0.008 CERK 0.63 0.033 0.006 0.014
CACNB1 1.51 0.045 0.014 0.017 A2M 0.62 0.015 0.016 0.010
FKBP1A 0.56 0.039 0.016 0.011 MDH1 0.60 0.050 0.017 0.011
Myogenesis/Fiber type pathways PECI 0.58 0.029 0.024 0.012
GDF8 3.65 0.025 0.032 0.007 MRPL35 0.57 0.040 0.043 0.037
IGF1 2.63 0.013 0.010 0.008 MRPS18B 0.56 0.009 0.002 0.001
IGFBP5 2.48 0.002 0.000 0.000 SLC25A20 0.55 0.044 0.049 0.022
PLCB1 2.34 0.028 0.014 0.007 CPT2 0.54 0.044 0.022 0.013
RASA4 2.26 0.037 0.027 0.029 MRPS12 0.53 0.044 0.008 0.010
PPP3CA 1.95 0.012 0.003 0.005 UCP2 0.51 0.030 0.023 0.015
PBX1 1.86 0.028 0.010 0.007 MLYCD 0.48 0.017 0.004 0.001
CALM1 1.70 0.005 0.004 0.008 PPIF 0.48 0.014 0.011 0.010
MBNL1 1.55 0.033 0.015 0.024 ADM 0.47 0.019 0.012 0.018
MEF2A 1.53 0.028 0.006 0.007 UCP3 0.47 0.014 0.010 0.007
NEO1 1.44 0.015 0.005 0.001 ALDH6A1 0.46 0.023 0.013 0.007
HMGB1 1.34 0.015 0.013 0.015 ACSL1 0.43 0.014 0.008 0.004
Extracellular Matrix GOT1 0.42 0.039 0.027 0.021
MFAP5 3.64 0.012 0.004 0.014 TST 0.41 0.015 0.002 0.001
COL4A3 2.89 0.043 0.014 0.019 MT1G 0.37 0.015 0.009 0.011
COL21A1 2.86 0.021 0.022 0.015 LPL 0.35 0.013 0.010 0.007
KAL1 2.57 0.002 0.003 0.003 RETSAT 0.35 0.002 0.006 0.005
MATN2 2.24 0.013 0.011 0.007 MT1M 0.34 0.015 0.006 0.004
CILP 2.09 0.035 0.043 0.034 MT1X 0.32 0.014 0.012 0.010
SMC3 1.88 0.021 0.026 0.019 GLUL 0.31 0.018 0.017 0.013
ECM2 1.86 0.037 0.035 0.021 MT2A 0.29 0.015 0.013 0.011
LAMB2 1.74 0.042 0.018 0.015 MT1H 0.29 0.015 0.015 0.012
COL4A1 0.51 0.048 0.032 0.015 MT1F 0.27 0.019 0.012 0.009
BSG 0.48 0.033 0.026 0.030 MT1E 0.26 0.012 0.006 0.005
COL4A2 0.43 0.012 0.010 0.006 LIPE 0.22 0.028 0.001 0.002
  1. Table of genes within function groups related to skeletal muscle. Groups defined by ratio is the expression ratio of CP:CTRL. P-values are listed for the three separate preprocessing algorithms used (MAS5, RMA, GCRMA).