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Table 4 Changes in pathways correlated with other muscle disease states

From: Novel transcriptional profile in wrist muscles from cerebral palsy patients

 

CP

DMD

IMB

HSP

 

MEAN

MEAN

CORR

MEAN

CORR

MEAN

CORR

NMJ

2.39

0.98

-0.24

1.19

-0.05

0.97

-0.02

ECC

0.66

0.90

0.12

1.26

0.14

1.39

0.62

MC

2.91

2.18

0.91

0.65

-0.74

1.07

-0.48

ECM

1.63

1.73

-0.23

0.69

0.44

0.66

0.02

FT

1.35

0.70

-0.21

0.92

0.37

0.91

-0.79

IGF1

1.19

1.58

N/A

1.04

N/A

0.76

N/A

MYG

1.14

1.11

-0.16

1.01

-0.24

1.01

-0.09

SCQ

1.19

1.18

-0.67

1.11

0.66

1.23

0.07

SCA

2.17

3.73

0.91

0.86

-0.81

0.94

-0.54

  1. Quantification of gene pathways in various disease states (CP, DMD, IMB, HSP). Quantification represents MEAN (geometric mean of expression ratios in specific muscle pathways defined in Figure 5 using inverse values for pathway inhibitors) and CORR (correlation of CP with the other disease states, reported with an R value). Satellite cells markers are separated into genes expressed in the quiescent (SCQ) and activated states (SCA).