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Table 4 Gene Ontology (GO) Annotation of genes analyzed in GeNorm

From: Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood

Gene Symbol Gene Name GO Biological Process Term GO Molecular Function Term GO Cellular Component Term
FPGS folylpolyglutamate synthase nucleobase, nucleoside, nucleotide and nucleic acid metabolic process glycine metabolic process one-carbon compound metabolic process biosynthetic process nucleoside metabolic process folic acid and derivative biosynthetic process nucleotide binding Tetrahydrofolylpoly- glutamate-synthase activity ATP binding ligase activity cytoplasm mitochondrion cytosol
TRAP1 TNF receptor-associated protein 1 protein folding nucleotide binding receptor activity tumor necrosis factor receptor binding ATP binding unfolded protein binding Mitochondrion
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial metabolic process oxidation reduction catalytic activity Binding 2,4-dienoyl-CoA reductase(NADPH) activity oxidoreductase activity mitochondrion
PPIB peptidylprolyl isomerase B (cyclophilin B) protein folding peptidyl-prolyl cis-trans isomerase activity protein binding isomerase activity peptide binding unfolded protein binding endoplasmic reticulum endoplasmic reticulum lumen melanosome
HMBS hydroxymethyl-bilane synthase porphyrin biosynthetic process heme biosynthetic process tetrapyrrole biosynthetic process hydroxymethylbilane synthase activity transferase activity cytoplasm
B2M beta-2-microglobulin antigen processing and presentation of peptide antigen via MHC class I immune response protein binding Golgi membrane extracellular region plasma membrane early endosome membrane MHC class I protein complex