Table 4 Gene Ontology (GO) Annotation of genes analyzed in GeNorm
Gene Symbol | Gene Name | GO Biological Process Term | GO Molecular Function Term | GO Cellular Component Term |
|---|---|---|---|---|
FPGS | folylpolyglutamate synthase | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process glycine metabolic process one-carbon compound metabolic process biosynthetic process nucleoside metabolic process folic acid and derivative biosynthetic process | nucleotide binding Tetrahydrofolylpoly- glutamate-synthase activity ATP binding ligase activity | cytoplasm mitochondrion cytosol |
TRAP1 | TNF receptor-associated protein 1 | protein folding | nucleotide binding receptor activity tumor necrosis factor receptor binding ATP binding unfolded protein binding | Mitochondrion |
DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | metabolic process oxidation reduction | catalytic activity Binding 2,4-dienoyl-CoA reductase(NADPH) activity oxidoreductase activity | mitochondrion |
PPIB | peptidylprolyl isomerase B (cyclophilin B) | protein folding | peptidyl-prolyl cis-trans isomerase activity protein binding isomerase activity peptide binding unfolded protein binding | endoplasmic reticulum endoplasmic reticulum lumen melanosome |
HMBS | hydroxymethyl-bilane synthase | porphyrin biosynthetic process heme biosynthetic process tetrapyrrole biosynthetic process | hydroxymethylbilane synthase activity transferase activity | cytoplasm |
B2M | beta-2-microglobulin | antigen processing and presentation of peptide antigen via MHC class I immune response | protein binding | Golgi membrane extracellular region plasma membrane early endosome membrane MHC class I protein complex |