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Table 4 Top 20 genes up-regulated in HCC

From: Gene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE

Tag UniGene Symbol Name Function Fold Change
ACCCGCCGGG Hs.335106 ZFYVE1 Zinc finger, FYVE domain containing 1 Transport 81
GATTTCTTTG Hs.435036 GPC3 Glypican 3 extracellular matrix 69
GCCAAGAATC Hs.307720 DTNB Dystrobrevin, beta Calcium and Zinc ion binding 56
CTAACTAGTT Hs.473583 NSEP1 Nuclease sensitive element binding protein 1 Response to external stimulus 50
GCTTGAATAA Hs.116724 AKR1B10 Aldo-keto reductase family 1, member B10 (aldose reductase) Steroid metabolism 47
GTGACCACGG Hs.436980 GRIN2C Glutamate receptor, ionotropic, N-methyl D-aspartate 2C Ion transport 39
CTCATCCTAC Hs.416049 TNPO2 Transportin 2 (importin 3, karyopherin beta 2b) Protein transport 36
GATGTATGTG Hs.461085   EST, strongly similar to NP_775842.1 Unclassified 36
ACCAGCACTC Hs.436911 AMBP Alpha-1-microglobulin/bikunin precursor Signal Transduction 32
CCGACGGGCG Hs.198161 PLA2G4B Phospholipase A2, group IVB (cytosolic) Signal Transduction 32
GGTCAGTCGG Hs.409352 FLJ20701 Hypothetical protein FLJ20701 Unclassified 29
ATGTAAAAAA Hs.429608 C5orf18 Chromosome 5 open reading frame 18 Unclassified 28
GACCCACCAT Hs.436911 AMBP Alpha-1-microglobulin/bikunin precursor Signal Transduction 28
CAAGTTTGCT Hs.439552 EEF1A1 Eukaryotic translation elongation factor 1 alpha 1 Signal Transduction 26
TTGTAAACTT Hs.509226 FKBP3 FK506 binding protein 3, 25kDa Cellular metabolism 25
GAAGGTGATC Hs.112208 XAGE-1 X antigen family, member 1 Cellular metabolism 25
GGGACGAGTG Hs.351316 TM4SF1 Transmembrane 4 L six family member 1 Unclassified 21
GAGGGTGGCG Hs.473847 SH3BGR SH3 domain binding glutamic acid-rich protein Cellular metabolism 18
TAAATACAGT Hs.221497 PRO0149 PRO0149 protein Unclassified 18
GTGGATGGAC Hs.6418 GPR175 G protein-coupled receptor 175 Organogenesis 17