Table 4 Top 20 genes up-regulated in HCC
From: Gene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE
Tag | UniGene | Symbol | Name | Function | Fold Change |
|---|---|---|---|---|---|
ACCCGCCGGG | Hs.335106 | ZFYVE1 | Zinc finger, FYVE domain containing 1 | Transport | 81 |
GATTTCTTTG | Hs.435036 | GPC3 | Glypican 3 | extracellular matrix | 69 |
GCCAAGAATC | Hs.307720 | DTNB | Dystrobrevin, beta | Calcium and Zinc ion binding | 56 |
CTAACTAGTT | Hs.473583 | NSEP1 | Nuclease sensitive element binding protein 1 | Response to external stimulus | 50 |
GCTTGAATAA | Hs.116724 | AKR1B10 | Aldo-keto reductase family 1, member B10 (aldose reductase) | Steroid metabolism | 47 |
GTGACCACGG | Hs.436980 | GRIN2C | Glutamate receptor, ionotropic, N-methyl D-aspartate 2C | Ion transport | 39 |
CTCATCCTAC | Hs.416049 | TNPO2 | Transportin 2 (importin 3, karyopherin beta 2b) | Protein transport | 36 |
GATGTATGTG | Hs.461085 | Â | EST, strongly similar to NP_775842.1 | Unclassified | 36 |
ACCAGCACTC | Hs.436911 | AMBP | Alpha-1-microglobulin/bikunin precursor | Signal Transduction | 32 |
CCGACGGGCG | Hs.198161 | PLA2G4B | Phospholipase A2, group IVB (cytosolic) | Signal Transduction | 32 |
GGTCAGTCGG | Hs.409352 | FLJ20701 | Hypothetical protein FLJ20701 | Unclassified | 29 |
ATGTAAAAAA | Hs.429608 | C5orf18 | Chromosome 5 open reading frame 18 | Unclassified | 28 |
GACCCACCAT | Hs.436911 | AMBP | Alpha-1-microglobulin/bikunin precursor | Signal Transduction | 28 |
CAAGTTTGCT | Hs.439552 | EEF1A1 | Eukaryotic translation elongation factor 1 alpha 1 | Signal Transduction | 26 |
TTGTAAACTT | Hs.509226 | FKBP3 | FK506 binding protein 3, 25kDa | Cellular metabolism | 25 |
GAAGGTGATC | Hs.112208 | XAGE-1 | X antigen family, member 1 | Cellular metabolism | 25 |
GGGACGAGTG | Hs.351316 | TM4SF1 | Transmembrane 4 L six family member 1 | Unclassified | 21 |
GAGGGTGGCG | Hs.473847 | SH3BGR | SH3 domain binding glutamic acid-rich protein | Cellular metabolism | 18 |
TAAATACAGT | Hs.221497 | PRO0149 | PRO0149 protein | Unclassified | 18 |
GTGGATGGAC | Hs.6418 | GPR175 | G protein-coupled receptor 175 | Organogenesis | 17 |