Table 5 Top 20 genes down-regulated in HCC
From: Gene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE
Tag | UniGene | Symbol | Name | Function | Fold Change |
|---|---|---|---|---|---|
GGCAGAGCCT | Hs.1955 | SAA2 | Serum amyloid A2 | Response to external stimulus | 56 |
TTAACTTTAT | Hs.368626 | RTN1 | Reticulon 1 | Signal Transduction | 56 |
TAAGCCCCGC | Hs.2899 | HPD | 4-hydroxyphenylpyruvate dioxygenase | Cellular metabolism | 49 |
GACACCGAGG | Hs.333383 | FCN3 | Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) | Transport | 44 |
TTGGCTAGAC | Hs.100914 | Cep192 | Centrosomal protein 192 kDa | Unclassified | 40 |
TTCCAGAGGC | Hs.8821 | HAMP | Hepcidin antimicrobial peptide | Cellular metabolism | 38 |
GATCCCAACT | Hs.418241 | MT2A | Metallothionein 2A | Metal Ion Binding | 37 |
AAGGACGCCG | Hs.117367 | SLC22A1 | Solute carrier family 22 (organic cation transporter), member 1 | Transport | 37 |
AACTCACAGA | Hs.168718 | AFM | Afamin | Transport | 36 |
AGAATAAGAA | Hs.418167 | ALB | Albumin | Regulation of body fluid (Blood coagulation) | 26 |
GCGGCCCCCC | Hs.839 | IGFALS | Insulin-like growth factor binding protein, acid labile subunit | Signal Transduction | 24 |
TACAGCCTGT | Hs.406184 | FGFR1OP2 | FGFR1 oncogene partner 2 | Unclassified | 24 |
CTTGGGTTTT | Hs.355888 | PLCB2 | Phospholipase C, beta 2 | Lipid metabolism | 24 |
CACTTCAAGG | Hs.521903 | LY6E | Lymphocyte antigen 6 complex, locus E | Signal Transduction | 23 |
CCACCCCGAA | Hs.35052 | TEGT | Testis enhanced gene transcript (BAX inhibitor 1) | Cell Death | 22 |
CCATTACCTC | Hs.134958 | RODH-4 | Retinol dehydrogenase 16 (all-trans and 13-cis) | Lipid metabolism | 21 |
AGTCTGGCCT | Hs.416707 | ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 | Response to external stimulus | 21 |
CCAGCAAGAG | Hs.11900 | ZGPAT | Zinc finger, CCCH-type with G patch domain | Unclassified | 20 |
AGAACCTTCC | Hs.181244 | HLA-A | Major histocompatibility complex, class I, A | Antigene presentation | 19 |
CCCTTCTTTG | Hs.356368 | HAO2 | Hydroxyacid oxidase 2 (long chain) | Cellular metabolism | 19 |