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Table 5 Top 20 genes down-regulated in HCC

From: Gene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE

Tag UniGene Symbol Name Function Fold Change
GGCAGAGCCT Hs.1955 SAA2 Serum amyloid A2 Response to external stimulus 56
TTAACTTTAT Hs.368626 RTN1 Reticulon 1 Signal Transduction 56
TAAGCCCCGC Hs.2899 HPD 4-hydroxyphenylpyruvate dioxygenase Cellular metabolism 49
GACACCGAGG Hs.333383 FCN3 Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) Transport 44
TTGGCTAGAC Hs.100914 Cep192 Centrosomal protein 192 kDa Unclassified 40
TTCCAGAGGC Hs.8821 HAMP Hepcidin antimicrobial peptide Cellular metabolism 38
GATCCCAACT Hs.418241 MT2A Metallothionein 2A Metal Ion Binding 37
AAGGACGCCG Hs.117367 SLC22A1 Solute carrier family 22 (organic cation transporter), member 1 Transport 37
AACTCACAGA Hs.168718 AFM Afamin Transport 36
AGAATAAGAA Hs.418167 ALB Albumin Regulation of body fluid (Blood coagulation) 26
GCGGCCCCCC Hs.839 IGFALS Insulin-like growth factor binding protein, acid labile subunit Signal Transduction 24
TACAGCCTGT Hs.406184 FGFR1OP2 FGFR1 oncogene partner 2 Unclassified 24
CTTGGGTTTT Hs.355888 PLCB2 Phospholipase C, beta 2 Lipid metabolism 24
CACTTCAAGG Hs.521903 LY6E Lymphocyte antigen 6 complex, locus E Signal Transduction 23
CCACCCCGAA Hs.35052 TEGT Testis enhanced gene transcript (BAX inhibitor 1) Cell Death 22
CCATTACCTC Hs.134958 RODH-4 Retinol dehydrogenase 16 (all-trans and 13-cis) Lipid metabolism 21
AGTCTGGCCT Hs.416707 ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 Response to external stimulus 21
CCAGCAAGAG Hs.11900 ZGPAT Zinc finger, CCCH-type with G patch domain Unclassified 20
AGAACCTTCC Hs.181244 HLA-A Major histocompatibility complex, class I, A Antigene presentation 19
CCCTTCTTTG Hs.356368 HAO2 Hydroxyacid oxidase 2 (long chain) Cellular metabolism 19