A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility

Table 2 Tumour cell percentage profile (TCP) performance.

	Median TCP profile index	P-value	Accuracy
Training cohorts (n = 165)
low pathological TCP (<30%)	-0.592		85%
medium/high pathological TCP (≥30%)	0.327	P < 0.0001	88%
Kappa score: 0.68 (95% 0.50 – 0.72)
Validation cohort (n = 238)
low pathological TCP (<30%)	-0.589		78%
medium/high pathological TCP (≥30%)	0.305	P < 0.0001	93%
Kappa score: 0.63 (95%CI 0.47–0.73)

P-value, Student's T-test; TCP Accuracy, accuracy between TCP profile assessment and pathological scoring.

ISSN: 1755-8794