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Table 1 Clinical data concerning primary neuroblastomas used in this study

From: Verification of genes differentially expressed in neuroblastoma tumours: a study of potential tumour suppressor genes

Group Case INSS INRGSS Age Outcome Ploidy MNA 1p del 11q del 17q gain OS Ver. Group Seq CNA
F 23R4 1 L         105 1 x  
  14E6MA 1 L         201 ni   
  18E8 1 L        WCG 169 1 x  
  31R8 1 L A        73 1   
  35R8 1 L I        50 1   
  26R9 1 L         91 2   
  16E1 1 L I   2n      190 2   
  37R6 1 L         37 2   
  20R9 2 L    2n    nd nd 113 1 x  
  33R7 2 L       nd nd 62 1 x  
  25R9 2 L A   2n      95 2   
  10R6 2 L    2n nd nd nd nd 160 2   
  13E8 2 L A        202 2   
  12E8MA 3 L    2n     WCG 209 0   
  15E3MA 3 L     Gain UB   WCG 195 0   
  21R6 4S MS    2n      111 2   
UF 19R6 3 L   DOD 2n y y   y 8 1 x  
  16R4MA 3 L A    y    y 131 0 x  
  9R9 3 M A DOD 2n   y y y 21 1 x x
  10R8 3 L A DOD 2n   y y y 59 2   x
  10R2MA 4 M I DOD 2n y y   y 12 0   
  15R3MA 4 M A DOD 2n   y nd y 9 0 x  
  12E6 4 M A DOD 2n y   nd (y) 9 1   
  13R0 4 M A DOD 2n y y   y 10 1   
  26R8 4 M I DOD 2n y y nd nd 18 1   
  29R2 4 M I   2n y y nd nd 85 1   
  11E1 4 M A   2n    y y 218 2   x
  26R0 4 M A   2n Gain y y y 93 2   
  34R0 4 M A DOD 2n     y 11 2   x
  39R1 ? M I   2n y y   y 29 2   x
  12E3 4 M I DOD 2n y y   y 4 2   x
  1. Column 1: Group, F = Favourable, UF = unfavourable; column 2: Case ID, MA = Cases used in the Microarray study; column 3: Clinical stage according to International Neuroblastoma Staging System (INSS) [2]; column 4: Clinical stage according to International Neuroblastoma Risk Group Staging System (INRGSS) [23], L = locoregional tumors, M = metastatic tumors, MS = metastases are confined to the skin, liver, and/or bone marrow in children younger than 18 months of age.; column 5: Age = Age at diagnosis, B = Below 12 months, I = Intermediate, i.e. 12–24 months, A = Above 24 months; column 6: Outcome: DOD = Dead of disease, nd = not determined; column 7: Ploidy: 2n = Diploidy; column 8: MNA = MYCN amplification, y = MNA, gain = MYCN< 4 times the ploidy; column 9: 1p del = 1p deletion, y = 1p del, UB = unbalanced; column 10: 11q del = 11q deletion, y = 11q del; column 11: y = 17q gain, WCG = whole chromosome gain, (y) = uncertain results; column 12: Overall survival (OS) in months; column 13: Verification groups (Ver.Group) with QPCR, 0 = Replicate group, 1 = Verification group 1, 2 = Verification group 2, ni = not included; column 14: Seq = Cases used for DNA Sequencing or Bisulphite Sequencing PCR (BSP) of POU4F2; column 15: CNA = Cases used for Copy Number Aberration analysis of CNTNAP2.