Skip to main content
Figure 1 | BMC Medical Genomics

Figure 1

From: Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells

Figure 1

Identification of genes whose expression significantly changed by clorgyline across the entire time course of 96 hr in E-CA-88 cells using Statistical Analysis of Microarrays (SAM). (A) SAM plot selected 216 clones (red dots) representing 156 unique named genes significantly upregulated at a false positive rate of 5%. (B) Gene expression profiles of these 216 clones across the time course. Each row represents a gene and each column represents a sample of control (C) or treated (T) cells. The order of the genes displayed is based on their ranks of significance determined by SAM. Positions of genes repressed by beta-catenin overexpression are indicated. The degree of color saturation corresponding to the ratio of gene expression is shown at the bottom of the image. Red indicates higher expression in experimental samples compared to the common reference sample, and green indicates lower expression.

Back to article page