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Figure 5 | BMC Medical Genomics

Figure 5

From: Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells

Figure 5

Clorgyline induced expression of secretory differentiation markers and decreased the proliferation capacity of E-CA-88 cells. (A) Expression of AR, PSA, and PSMA, three well-known secretory cell markers, were upregulated by clorgyline in E-CA-88 cells as determined by qRT-PCR. (B) The proliferation capacity of E-CA-88 cells was significantly decreased after 6, 24, and 96 hr of clorgyline-treatment compared to control cells. For both (A) and (B), asterisk indicates statistical significance by t-test.

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BMC Medical Genomics

ISSN: 1755-8794

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